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The role of inflammation in driving left ventricular remodeling in a pre-HFpEF model.
Loredo-Mendoza ML, Ramirez-Sanchez I, Bustamante-Pozo MM, Ayala M, Navarrete V, Garate-Carrillo A, Ito BR, Ceballos G, Omens J, Villarreal F. Loredo-Mendoza ML, et al. Among authors: ito br. Exp Biol Med (Maywood). 2020 Apr;245(8):748-757. doi: 10.1177/1535370220912699. Epub 2020 Mar 17. Exp Biol Med (Maywood). 2020. PMID: 32183553 Free PMC article.
Preservation of Post-Infarction Cardiac Structure and Function via Long-Term Oral Formyl Peptide Receptor Agonist Treatment.
García RA, Ito BR, Lupisella JA, Carson NA, Hsu MY, Fernando G, Heroux M, Bouvier M, Dierks E, Kick EK, Gordon DA, Chen J, Mintier G, Carrier M, St-Onge S, Shah H, Towne J, Bucardo MS, Ma X, Ryan CS, Wurtz NR, Ostrowski J, Villarreal FJ. García RA, et al. Among authors: ito br. JACC Basic Transl Sci. 2019 Nov 13;4(8):905-920. doi: 10.1016/j.jacbts.2019.07.005. eCollection 2019 Dec. JACC Basic Transl Sci. 2019. PMID: 31909300 Free PMC article.
Discovery of BMS-986235/LAR-1219: A Potent Formyl Peptide Receptor 2 (FPR2) Selective Agonist for the Prevention of Heart Failure.
Asahina Y, Wurtz NR, Arakawa K, Carson N, Fujii K, Fukuchi K, Garcia R, Hsu MY, Ishiyama J, Ito B, Kick E, Lupisella J, Matsushima S, Ohata K, Ostrowski J, Saito Y, Tsuda K, Villarreal F, Yamada H, Yamaoka T, Wexler R, Gordon D, Kohno Y. Asahina Y, et al. J Med Chem. 2020 Sep 10;63(17):9003-9019. doi: 10.1021/acs.jmedchem.9b02101. Epub 2020 May 24. J Med Chem. 2020. PMID: 32407089
Targeting thyroid hormone receptor-beta agonists to the liver reduces cholesterol and triglycerides and improves the therapeutic index.
Erion MD, Cable EE, Ito BR, Jiang H, Fujitaki JM, Finn PD, Zhang BH, Hou J, Boyer SH, van Poelje PD, Linemeyer DL. Erion MD, et al. Among authors: ito br. Proc Natl Acad Sci U S A. 2007 Sep 25;104(39):15490-5. doi: 10.1073/pnas.0702759104. Epub 2007 Sep 18. Proc Natl Acad Sci U S A. 2007. PMID: 17878314 Free PMC article.
35 results