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Structural locations and functional roles of new subsites S5, S6, and S7 in memapsin 2 (beta-secretase).
Biochemistry. 2005 Jan 11;44(1):105-12. doi: 10.1021/bi048106k.
Biochemistry. 2005.
PMID: 15628850
Internalization of exogenously added memapsin 2 (beta-secretase) ectodomain by cells is mediated by amyloid precursor protein.
Huang XP, Chang WP, Koelsch G, Turner RT 3rd, Lupu F, Tang J.
Huang XP, et al. Among authors: turner rt 3rd.
J Biol Chem. 2004 Sep 3;279(36):37886-94. doi: 10.1074/jbc.M402130200. Epub 2004 Jun 14.
J Biol Chem. 2004.
PMID: 15197182
Free article.
Item in Clipboard
Memapsin 2, a drug target for Alzheimer's disease.
Koelsch G, Turner RT 3rd, Hong L, Ghosh AK, Tang J.
Koelsch G, et al. Among authors: turner rt 3rd.
Biochem Soc Symp. 2003;(70):213-20. doi: 10.1042/bss0700213.
Biochem Soc Symp. 2003.
PMID: 14587294
Review.
Item in Clipboard
Study of memapsin 2 (beta-secretase) and strategy of inhibitor design.
Tang J, Ghosh AK, Hong L, Koelsch G, Turner RT 3rd, Chang W.
Tang J, et al. Among authors: turner rt 3rd.
J Mol Neurosci. 2003;20(3):299-304. doi: 10.1385/JMN:20:3:299.
J Mol Neurosci. 2003.
PMID: 14501012
Review.
Item in Clipboard
Crystal structure of memapsin 2 (beta-secretase) in complex with an inhibitor OM00-3.
Hong L, Turner RT 3rd, Koelsch G, Shin D, Ghosh AK, Tang J.
Hong L, et al. Among authors: turner rt 3rd.
Biochemistry. 2002 Sep 10;41(36):10963-7. doi: 10.1021/bi026232n.
Biochemistry. 2002.
PMID: 12206667
Item in Clipboard
Memapsin 2 (beta-secretase) as a therapeutic target.
Hong L, Turner RT 3rd, Koelsch G, Ghosh AK, Tang J.
Hong L, et al. Among authors: turner rt 3rd.
Biochem Soc Trans. 2002 Aug;30(4):530-4. doi: 10.1042/bst0300530.
Biochem Soc Trans. 2002.
PMID: 12196130
Review.
Item in Clipboard
Specificity of memapsin 1 and its implications on the design of memapsin 2 (beta-secretase) inhibitor selectivity.
Turner RT 3rd, Loy JA, Nguyen C, Devasamudram T, Ghosh AK, Koelsch G, Tang J.
Turner RT 3rd, et al.
Biochemistry. 2002 Jul 9;41(27):8742-6. doi: 10.1021/bi025926t.
Biochemistry. 2002.
PMID: 12093293
Item in Clipboard
Subsite specificity of memapsin 2 (beta-secretase): implications for inhibitor design.
Turner RT 3rd, Koelsch G, Hong L, Castanheira P, Ermolieff J, Ghosh AK, Tang J.
Turner RT 3rd, et al.
Biochemistry. 2001 Aug 28;40(34):10001-6. doi: 10.1021/bi015546s.
Biochemistry. 2001.
PMID: 11513577
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