Chu CS - Search Results

1

Extensive posttranscriptional deletion of the coding sequences for part of nucleotide-binding fold 1 in respiratory epithelial mRNA transcripts of the cystic fibrosis transmembrane conductance regulator gene is not associated with the clinical manifestations of cystic fibrosis.

Chu CS, Trapnell BC, Curristin SM, Cutting GR, Crystal RG. Chu CS, et al. J Clin Invest. 1992 Sep;90(3):785-90. doi: 10.1172/JCI115952. J Clin Invest. 1992. PMID: 1381723 Free PMC article.

2

Down-regulation of cystic fibrosis transmembrane conductance regulator gene expression by agents that modulate intracellular divalent cations.

Bargon J, Trapnell BC, Chu CS, Rosenthal ER, Yoshimura K, Guggino WB, Dalemans W, Pavirani A, Lecocq JP, Crystal RG. Bargon J, et al. Among authors: chu cs. Mol Cell Biol. 1992 Apr;12(4):1872-8. doi: 10.1128/mcb.12.4.1872-1878.1992. Mol Cell Biol. 1992. PMID: 1372390 Free PMC article.

3

Variable deletion of exon 9 coding sequences in cystic fibrosis transmembrane conductance regulator gene mRNA transcripts in normal bronchial epithelium.

Chu CS, Trapnell BC, Murtagh JJ Jr, Moss J, Dalemans W, Jallat S, Mercenier A, Pavirani A, Lecocq JP, Cutting GR, et al. Chu CS, et al. EMBO J. 1991 Jun;10(6):1355-63. doi: 10.1002/j.1460-2075.1991.tb07655.x. EMBO J. 1991. PMID: 1709095 Free PMC article.

4

Expression of the cystic fibrosis transmembrane conductance regulator gene in the respiratory tract of normal individuals and individuals with cystic fibrosis.

Trapnell BC, Chu CS, Paakko PK, Banks TC, Yoshimura K, Ferrans VJ, Chernick MS, Crystal RG. Trapnell BC, et al. Among authors: chu cs. Proc Natl Acad Sci U S A. 1991 Aug 1;88(15):6565-9. doi: 10.1073/pnas.88.15.6565. Proc Natl Acad Sci U S A. 1991. PMID: 1713683 Free PMC article.

5

Expression of the cystic fibrosis transmembrane conductance regulator gene in cells of non-epithelial origin.

Yoshimura K, Nakamura H, Trapnell BC, Chu CS, Dalemans W, Pavirani A, Lecocq JP, Crystal RG. Yoshimura K, et al. Among authors: chu cs. Nucleic Acids Res. 1991 Oct 11;19(19):5417-23. doi: 10.1093/nar/19.19.5417. Nucleic Acids Res. 1991. PMID: 1717947 Free PMC article.

6

Down-regulation of cystic fibrosis gene mRNA transcript levels and induction of the cystic fibrosis chloride secretory phenotype in epithelial cells by phorbol ester.

Trapnell BC, Zeitlin PL, Chu CS, Yoshimura K, Nakamura H, Guggino WB, Bargon J, Banks TC, Dalemans W, Pavirani A, et al. Trapnell BC, et al. Among authors: chu cs. J Biol Chem. 1991 Jun 5;266(16):10319-23. J Biol Chem. 1991. PMID: 2037584 Free article.

7

Gene transfer to freshly isolated human respiratory epithelial cells in vitro using a replication-deficient adenovirus containing the human cystic fibrosis transmembrane conductance regulator cDNA.

Rosenfeld MA, Chu CS, Seth P, Danel C, Banks T, Yoneyama K, Yoshimura K, Crystal RG. Rosenfeld MA, et al. Among authors: chu cs. Hum Gene Ther. 1994 Mar;5(3):331-42. doi: 10.1089/hum.1994.5.3-331. Hum Gene Ther. 1994. PMID: 7517189

8

Administration of an adenovirus containing the human CFTR cDNA to the respiratory tract of individuals with cystic fibrosis.

Crystal RG, McElvaney NG, Rosenfeld MA, Chu CS, Mastrangeli A, Hay JG, Brody SL, Jaffe HA, Eissa NT, Danel C. Crystal RG, et al. Among authors: chu cs. Nat Genet. 1994 Sep;8(1):42-51. doi: 10.1038/ng0994-42. Nat Genet. 1994. PMID: 7527271 Clinical Trial.

9

Alternative splicing of intron 23 of the human cystic fibrosis transmembrane conductance regulator gene resulting in a novel exon and transcript coding for a shortened intracytoplasmic C terminus.

Yoshimura K, Chu CS, Crystal RG. Yoshimura K, et al. Among authors: chu cs. J Biol Chem. 1993 Jan 5;268(1):686-90. J Biol Chem. 1993. PMID: 7678008 Free article.

10

Genetic basis of variable exon 9 skipping in cystic fibrosis transmembrane conductance regulator mRNA.

Chu CS, Trapnell BC, Curristin S, Cutting GR, Crystal RG. Chu CS, et al. Nat Genet. 1993 Feb;3(2):151-6. doi: 10.1038/ng0293-151. Nat Genet. 1993. PMID: 7684646

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