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Molecular diversity through sugar scaffolds.
Le GT, Abbenante G, Becker B, Grathwohl M, Halliday J, Tometzki G, Zuegg J, Meutermans W. Le GT, et al. Among authors: zuegg j. Drug Discov Today. 2003 Aug 1;8(15):701-9. doi: 10.1016/s1359-6446(03)02751-x. Drug Discov Today. 2003. PMID: 12927513 Review.
A versatile synthetic approach toward diversity libraries using monosaccharide scaffolds.
Thanh GL, Abbenante G, Adamson G, Becker B, Clark C, Condie G, Falzun T, Grathwohl M, Gupta P, Hanson M, Huynh N, Katavic P, Kuipers K, Lam A, Liu L, Mann M, Mason J, McKeveney D, Muldoon C, Pearson A, Rajaratnam P, Ryan S, Tometzki G, Verquin G, Waanders J, West M, Wilcox N, Wimmer N, Yau A, Zuegg J, Meutermans W. Thanh GL, et al. Among authors: zuegg j. J Org Chem. 2010 Jan 1;75(1):197-203. doi: 10.1021/jo9021919. J Org Chem. 2010. PMID: 19961235
Biological diversity from a structurally diverse library: systematically scanning conformational space using a pyranose scaffold.
Abbenante G, Becker B, Blanc S, Clark C, Condie G, Fraser G, Grathwohl M, Halliday J, Henderson S, Lam A, Liu L, Mann M, Muldoon C, Pearson A, Premraj R, Ramsdale T, Rossetti T, Schafer K, Le Thanh G, Tometzki G, Vari F, Verquin G, Waanders J, West M, Wimmer N, Yau A, Zuegg J, Meutermans W. Abbenante G, et al. Among authors: zuegg j. J Med Chem. 2010 Aug 12;53(15):5576-86. doi: 10.1021/jm1002777. J Med Chem. 2010. PMID: 20684600
Carbohydrate scaffolds as glycosyltransferase inhibitors with in vivo antibacterial activity.
Zuegg J, Muldoon C, Adamson G, McKeveney D, Le Thanh G, Premraj R, Becker B, Cheng M, Elliott AG, Huang JX, Butler MS, Bajaj M, Seifert J, Singh L, Galley NF, Roper DI, Lloyd AJ, Dowson CG, Cheng TJ, Cheng WC, Demon D, Meyer E, Meutermans W, Cooper MA. Zuegg J, et al. Nat Commun. 2015 Jul 21;6:7719. doi: 10.1038/ncomms8719. Nat Commun. 2015. PMID: 26194781 Free PMC article.
Structure aided design of chimeric antibiotics.
Karoli T, Mamidyala SK, Zuegg J, Fry SR, Tee EH, Bradford TA, Madala PK, Huang JX, Ramu S, Butler MS, Cooper MA. Karoli T, et al. Among authors: zuegg j. Bioorg Med Chem Lett. 2012 Apr 1;22(7):2428-33. doi: 10.1016/j.bmcl.2012.02.019. Epub 2012 Feb 22. Bioorg Med Chem Lett. 2012. PMID: 22406152
56 results