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Molecular diversity through sugar scaffolds.
Le GT, Abbenante G, Becker B, Grathwohl M, Halliday J, Tometzki G, Zuegg J, Meutermans W. Le GT, et al. Among authors: meutermans w. Drug Discov Today. 2003 Aug 1;8(15):701-9. doi: 10.1016/s1359-6446(03)02751-x. Drug Discov Today. 2003. PMID: 12927513 Review.
Carbohydrates as scaffolds in drug discovery.
Meutermans W, Le GT, Becker B. Meutermans W, et al. ChemMedChem. 2006 Nov;1(11):1164-94. doi: 10.1002/cmdc.200600150. ChemMedChem. 2006. PMID: 16983718 Review.
Carbohydrate-based scaffolds in drug discovery.
Becker B, Condie GC, Le GT, Meutermans W. Becker B, et al. Among authors: meutermans w. Mini Rev Med Chem. 2006 Dec;6(12):1299-309. doi: 10.2174/138955706778993003. Mini Rev Med Chem. 2006. PMID: 17168806 Review.
A versatile synthetic approach toward diversity libraries using monosaccharide scaffolds.
Thanh GL, Abbenante G, Adamson G, Becker B, Clark C, Condie G, Falzun T, Grathwohl M, Gupta P, Hanson M, Huynh N, Katavic P, Kuipers K, Lam A, Liu L, Mann M, Mason J, McKeveney D, Muldoon C, Pearson A, Rajaratnam P, Ryan S, Tometzki G, Verquin G, Waanders J, West M, Wilcox N, Wimmer N, Yau A, Zuegg J, Meutermans W. Thanh GL, et al. Among authors: meutermans w. J Org Chem. 2010 Jan 1;75(1):197-203. doi: 10.1021/jo9021919. J Org Chem. 2010. PMID: 19961235
Biological diversity from a structurally diverse library: systematically scanning conformational space using a pyranose scaffold.
Abbenante G, Becker B, Blanc S, Clark C, Condie G, Fraser G, Grathwohl M, Halliday J, Henderson S, Lam A, Liu L, Mann M, Muldoon C, Pearson A, Premraj R, Ramsdale T, Rossetti T, Schafer K, Le Thanh G, Tometzki G, Vari F, Verquin G, Waanders J, West M, Wimmer N, Yau A, Zuegg J, Meutermans W. Abbenante G, et al. Among authors: meutermans w. J Med Chem. 2010 Aug 12;53(15):5576-86. doi: 10.1021/jm1002777. J Med Chem. 2010. PMID: 20684600
Carbohydrate scaffolds as glycosyltransferase inhibitors with in vivo antibacterial activity.
Zuegg J, Muldoon C, Adamson G, McKeveney D, Le Thanh G, Premraj R, Becker B, Cheng M, Elliott AG, Huang JX, Butler MS, Bajaj M, Seifert J, Singh L, Galley NF, Roper DI, Lloyd AJ, Dowson CG, Cheng TJ, Cheng WC, Demon D, Meyer E, Meutermans W, Cooper MA. Zuegg J, et al. Among authors: meutermans w. Nat Commun. 2015 Jul 21;6:7719. doi: 10.1038/ncomms8719. Nat Commun. 2015. PMID: 26194781 Free PMC article.
Targeting the forgotten transglycosylases.
Halliday J, McKeveney D, Muldoon C, Rajaratnam P, Meutermans W. Halliday J, et al. Among authors: meutermans w. Biochem Pharmacol. 2006 Mar 30;71(7):957-67. doi: 10.1016/j.bcp.2005.10.030. Epub 2005 Nov 18. Biochem Pharmacol. 2006. PMID: 16298347 Review.
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