Middleton B - Search Results

1

Dynamic contrast-enhanced MRI of vascular changes induced by the VEGF-signalling inhibitor ZD4190 in human tumour xenografts.

Checkley D, Tessier JJ, Wedge SR, Dukes M, Kendrew J, Curry B, Middleton B, Waterton JC. Checkley D, et al. Among authors: middleton b. Magn Reson Imaging. 2003 Jun;21(5):475-82. doi: 10.1016/s0730-725x(02)00644-6. Magn Reson Imaging. 2003. PMID: 12878256

2

Diurnal variation in the femoral articular cartilage of the knee in young adult humans.

Waterton JC, Solloway S, Foster JE, Keen MC, Gandy S, Middleton BJ, Maciewicz RA, Watt I, Dieppe PA, Taylor CJ. Waterton JC, et al. Among authors: middleton bj. Magn Reson Med. 2000 Jan;43(1):126-32. doi: 10.1002/(sici)1522-2594(200001)43:1<126::aid-mrm15>3.0.co;2-#. Magn Reson Med. 2000. PMID: 10642739 Free article. Clinical Trial.

3

1H-NMR spectroscopy as a means of monitoring nephrotoxicity as exemplified by studies with cephaloridine.

Murgatroyd LB, Pickford RJ, Smith IK, Wilson ID, Middleton BJ. Murgatroyd LB, et al. Among authors: middleton bj. Hum Exp Toxicol. 1992 Jan;11(1):35-41. doi: 10.1177/096032719201100105. Hum Exp Toxicol. 1992. PMID: 1354458

4

Pathological and morphometric assessment of testicular parameters in patients with metastatic prostate cancer following treatment with either the antiandrogen Casodex (ZM176,334) or bilateral orchidectomy.

Jones HB, Betton GR, Bowdler AL, McFarquhar RL, Middleton BJ, Lunglmayr G. Jones HB, et al. Among authors: middleton bj. Urol Res. 1994;22(3):191-5. doi: 10.1007/BF00571849. Urol Res. 1994. PMID: 7992465 Clinical Trial.

5

Identification of in vitro folding conditions for procathepsin S and cathepsin S using fractional factorial screens.

Tobbell DA, Middleton BJ, Raines S, Needham MR, Taylor IW, Beveridge JY, Abbott WM. Tobbell DA, et al. Protein Expr Purif. 2002 Mar;24(2):242-54. doi: 10.1006/prep.2001.1573. Protein Expr Purif. 2002. PMID: 11858719

6

Validation and development of fluorescence two-dimensional differential gel electrophoresis proteomics technology.

Tonge R, Shaw J, Middleton B, Rowlinson R, Rayner S, Young J, Pognan F, Hawkins E, Currie I, Davison M. Tonge R, et al. Among authors: middleton b. Proteomics. 2001 Mar;1(3):377-96. doi: 10.1002/1615-9861(200103)1:3<377::AID-PROT377>3.0.CO;2-6. Proteomics. 2001. PMID: 11680884

7

In vitro approach to assess the potential for risk of idiosyncratic adverse reactions caused by candidate drugs.

Thompson RA, Isin EM, Li Y, Weidolf L, Page K, Wilson I, Swallow S, Middleton B, Stahl S, Foster AJ, Dolgos H, Weaver R, Kenna JG. Thompson RA, et al. Among authors: middleton b. Chem Res Toxicol. 2012 Aug 20;25(8):1616-32. doi: 10.1021/tx300091x. Epub 2012 May 31. Chem Res Toxicol. 2012. PMID: 22646477

8

Relationship between QT interval and heart rate in Alderley Park beagles.

Davis AS, Middleton BJ. Davis AS, et al. Among authors: middleton bj. Vet Rec. 1999 Aug 28;145(9):248-50. doi: 10.1136/vr.145.9.248. Vet Rec. 1999. PMID: 10504067

9

Utility of spherical human liver microtissues for prediction of clinical drug-induced liver injury.

Proctor WR, Foster AJ, Vogt J, Summers C, Middleton B, Pilling MA, Shienson D, Kijanska M, Ströbel S, Kelm JM, Morgan P, Messner S, Williams D. Proctor WR, et al. Among authors: middleton b. Arch Toxicol. 2017 Aug;91(8):2849-2863. doi: 10.1007/s00204-017-2002-1. Epub 2017 Jun 13. Arch Toxicol. 2017. PMID: 28612260 Free PMC article.

10

High-throughput metabolic stability studies in drug discovery by orthogonal acceleration time-of-flight (OATOF) with analogue-to-digital signal capture (ADC).

Temesi DG, Martin S, Smith R, Jones C, Middleton B. Temesi DG, et al. Among authors: middleton b. Rapid Commun Mass Spectrom. 2010 Jun 30;24(12):1730-6. doi: 10.1002/rcm.4546. Rapid Commun Mass Spectrom. 2010. PMID: 20499316

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