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Novel IKK inhibitors: beta-carbolines.
Bioorg Med Chem Lett. 2003 Jul 21;13(14):2419-22. doi: 10.1016/s0960-894x(03)00408-6.
Bioorg Med Chem Lett. 2003.
PMID: 12824047
Nedd8 modification of cul-1 activates SCF(beta(TrCP))-dependent ubiquitination of IkappaBalpha.
Read MA, Brownell JE, Gladysheva TB, Hottelet M, Parent LA, Coggins MB, Pierce JW, Podust VN, Luo RS, Chau V, Palombella VJ.
Read MA, et al. Among authors: hottelet m.
Mol Cell Biol. 2000 Apr;20(7):2326-33. doi: 10.1128/MCB.20.7.2326-2333.2000.
Mol Cell Biol. 2000.
PMID: 10713156
Free PMC article.
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Small molecule inhibitors of IkappaB kinase are selectively toxic for subgroups of diffuse large B-cell lymphoma defined by gene expression profiling.
Lam LT, Davis RE, Pierce J, Hepperle M, Xu Y, Hottelet M, Nong Y, Wen D, Adams J, Dang L, Staudt LM.
Lam LT, et al. Among authors: hottelet m.
Clin Cancer Res. 2005 Jan 1;11(1):28-40.
Clin Cancer Res. 2005.
PMID: 15671525
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The 72-kDa component of signal recognition particle is cleaved during apoptosis.
Utz PJ, Hottelet M, Le TM, Kim SJ, Geiger ME, van Venrooij WJ, Anderson P.
Utz PJ, et al. Among authors: hottelet m.
J Biol Chem. 1998 Dec 25;273(52):35362-70. doi: 10.1074/jbc.273.52.35362.
J Biol Chem. 1998.
PMID: 9857079
Free article.
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Association of phosphorylated serine/arginine (SR) splicing factors with the U1-small ribonucleoprotein (snRNP) autoantigen complex accompanies apoptotic cell death.
Utz PJ, Hottelet M, van Venrooij WJ, Anderson P.
Utz PJ, et al. Among authors: hottelet m.
J Exp Med. 1998 Feb 16;187(4):547-60. doi: 10.1084/jem.187.4.547.
J Exp Med. 1998.
PMID: 9463405
Free PMC article.
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Monoclonal antibodies derived from BALB/c mice immunized with apoptotic Jurkat T cells recognize known autoantigens.
Gensler TJ, Hottelet M, Zhang C, Schlossman S, Anderson P, Utz PJ.
Gensler TJ, et al. Among authors: hottelet m.
J Autoimmun. 2001 Feb;16(1):59-69. doi: 10.1006/jaut.2000.0464.
J Autoimmun. 2001.
PMID: 11221997
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Proteins phosphorylated during stress-induced apoptosis are common targets for autoantibody production in patients with systemic lupus erythematosus.
Utz PJ, Hottelet M, Schur PH, Anderson P.
Utz PJ, et al. Among authors: hottelet m.
J Exp Med. 1997 Mar 3;185(5):843-54. doi: 10.1084/jem.185.5.843.
J Exp Med. 1997.
PMID: 9120390
Free PMC article.
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