A mutation in the extracellular domain of the insulin receptor impairs the ability of insulin to stimulate receptor autophosphorylation.
Accili D, Mosthaf L, Ullrich A, Taylor SI.
Accili D, et al.
J Biol Chem. 1991 Jan 5;266(1):434-9.
J Biol Chem. 1991.
PMID: 1845971
Free article.
We have previously reported that a mutation substituting valine for Phe382 in the alpha-subunit of the insulin receptor is associated with impaired transport of the mutant receptor to the plasma membrane (Accili, D., Frapier, C., Mosthaf, L., McKeon, C., Elbein, S. …
We have previously reported that a mutation substituting valine for Phe382 in the alpha-subunit of the insulin receptor is associated with i …