Trevillyan J - Search Results

1

PTP1B antisense-treated mice show regulation of genes involved in lipogenesis in liver and fat.

Waring JF, Ciurlionis R, Clampit JE, Morgan S, Gum RJ, Jolly RA, Kroeger P, Frost L, Trevillyan J, Zinker BA, Jirousek M, Ulrich RG, Rondinone CM. Waring JF, et al. Among authors: trevillyan j. Mol Cell Endocrinol. 2003 May 30;203(1-2):155-68. doi: 10.1016/s0303-7207(03)00008-x. Mol Cell Endocrinol. 2003. PMID: 12782412

2

Protein tyrosine phosphatase 1B reduction regulates adiposity and expression of genes involved in lipogenesis.

Rondinone CM, Trevillyan JM, Clampit J, Gum RJ, Berg C, Kroeger P, Frost L, Zinker BA, Reilly R, Ulrich R, Butler M, Monia BP, Jirousek MR, Waring JF. Rondinone CM, et al. Among authors: trevillyan jm. Diabetes. 2002 Aug;51(8):2405-11. doi: 10.2337/diabetes.51.8.2405. Diabetes. 2002. PMID: 12145151

3

PTP1B antisense oligonucleotide lowers PTP1B protein, normalizes blood glucose, and improves insulin sensitivity in diabetic mice.

Zinker BA, Rondinone CM, Trevillyan JM, Gum RJ, Clampit JE, Waring JF, Xie N, Wilcox D, Jacobson P, Frost L, Kroeger PE, Reilly RM, Koterski S, Opgenorth TJ, Ulrich RG, Crosby S, Butler M, Murray SF, McKay RA, Bhanot S, Monia BP, Jirousek MR. Zinker BA, et al. Among authors: trevillyan jm. Proc Natl Acad Sci U S A. 2002 Aug 20;99(17):11357-62. doi: 10.1073/pnas.142298199. Epub 2002 Aug 8. Proc Natl Acad Sci U S A. 2002. PMID: 12169659 Free PMC article.

4

Protein tyrosine phosphatase 1B negatively regulates leptin signaling in a hypothalamic cell line.

Kaszubska W, Falls HD, Schaefer VG, Haasch D, Frost L, Hessler P, Kroeger PE, White DW, Jirousek MR, Trevillyan JM. Kaszubska W, et al. Mol Cell Endocrinol. 2002 Sep 30;195(1-2):109-18. doi: 10.1016/s0303-7207(02)00178-8. Mol Cell Endocrinol. 2002. PMID: 12354677

5

Reduction of protein tyrosine phosphatase 1B increases insulin-dependent signaling in ob/ob mice.

Gum RJ, Gaede LL, Koterski SL, Heindel M, Clampit JE, Zinker BA, Trevillyan JM, Ulrich RG, Jirousek MR, Rondinone CM. Gum RJ, et al. Among authors: trevillyan jm. Diabetes. 2003 Jan;52(1):21-8. doi: 10.2337/diabetes.52.1.21. Diabetes. 2003. PMID: 12502489

6

Reduction of protein-tyrosine phosphatase-1B increases insulin signaling in FAO hepatoma cells.

Clampit JE, Meuth JL, Smith HT, Reilly RM, Jirousek MR, Trevillyan JM, Rondinone CM. Clampit JE, et al. Biochem Biophys Res Commun. 2003 Jan 10;300(2):261-7. doi: 10.1016/s0006-291x(02)02839-5. Biochem Biophys Res Commun. 2003. PMID: 12504077

7

Antisense protein tyrosine phosphatase 1B reverses activation of p38 mitogen-activated protein kinase in liver of ob/ob mice.

Gum RJ, Gaede LL, Heindel MA, Waring JF, Trevillyan JM, Zinker BA, Stark ME, Wilcox D, Jirousek MR, Rondinone CM, Ulrich RG. Gum RJ, et al. Among authors: trevillyan jm. Mol Endocrinol. 2003 Jun;17(6):1131-43. doi: 10.1210/me.2002-0288. Epub 2003 Mar 20. Mol Endocrinol. 2003. PMID: 12649327

8

Reduction of PTP1B induces differential expression of PI3-kinase (p85alpha) isoforms.

Rondinone CM, Clampit J, Gum RJ, Zinker BA, Jirousek MR, Trevillyan JM. Rondinone CM, et al. Among authors: trevillyan jm. Biochem Biophys Res Commun. 2004 Oct 15;323(2):652-9. doi: 10.1016/j.bbrc.2004.08.138. Biochem Biophys Res Commun. 2004. PMID: 15369800

9

In vitro enzymatic assays of protein tyrosine phosphatase 1B.

Lubben T, Clampit J, Stashko M, Trevillyan J, Jirousek MR. Lubben T, et al. Among authors: trevillyan j. Curr Protoc Pharmacol. 2001 Aug;Chapter 3:Unit3.8. doi: 10.1002/0471141755.ph0308s13. Curr Protoc Pharmacol. 2001. PMID: 21959757

10

Discovery and structure-activity relationship of oxalylarylaminobenzoic acids as inhibitors of protein tyrosine phosphatase 1B.

Liu G, Szczepankiewicz BG, Pei Z, Janowick DA, Xin Z, Hajduk PJ, Abad-Zapatero C, Liang H, Hutchins CW, Fesik SW, Ballaron SJ, Stashko MA, Lubben T, Mika AK, Zinker BA, Trevillyan JM, Jirousek MR. Liu G, et al. Among authors: trevillyan jm. J Med Chem. 2003 May 22;46(11):2093-103. doi: 10.1021/jm0205696. J Med Chem. 2003. PMID: 12747781

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