Piper SC - Search Results

1

Peptide-based, irreversible inhibitors of gamma-secretase activity.

Piper SC, Amtul Z, Galiñanes-Garcia L, Howard VG, Ziani-Cherif C, McLendon C, Rochette MJ, Fauq A, Golde TE, Murphy MP. Piper SC, et al. Biochem Biophys Res Commun. 2003 Jun 6;305(3):529-33. doi: 10.1016/s0006-291x(03)00828-3. Biochem Biophys Res Commun. 2003. PMID: 12763025

2

Overexpression of nicastrin increases Abeta production.

Murphy MP, Das P, Nyborg AC, Rochette MJ, Dodson MW, Loosbrock NM, Souder TM, McLendon C, Merit SL, Piper SC, Jansen KR, Golde TE. Murphy MP, et al. Among authors: piper sc. FASEB J. 2003 Jun;17(9):1138-40. doi: 10.1096/fj.02-1050fje. Epub 2003 Apr 8. FASEB J. 2003. PMID: 12692078

3

A presenilin 1 mutation associated with familial frontotemporal dementia inhibits gamma-secretase cleavage of APP and notch.

Amtul Z, Lewis PA, Piper S, Crook R, Baker M, Findlay K, Singleton A, Hogg M, Younkin L, Younkin SG, Hardy J, Hutton M, Boeve BF, Tang-Wai D, Golde TE. Amtul Z, et al. Neurobiol Dis. 2002 Mar;9(2):269-73. doi: 10.1006/nbdi.2001.0473. Neurobiol Dis. 2002. PMID: 11895378

4

Expression of BRI-amyloid beta peptide fusion proteins: a novel method for specific high-level expression of amyloid beta peptides.

Lewis PA, Piper S, Baker M, Onstead L, Murphy MP, Hardy J, Wang R, McGowan E, Golde TE. Lewis PA, et al. Biochim Biophys Acta. 2001 Jul 27;1537(1):58-62. doi: 10.1016/s0925-4439(01)00054-0. Biochim Biophys Acta. 2001. PMID: 11476963 Free article.

5

A non-canonical ESCRT pathway, including histidine domain phosphotyrosine phosphatase (HD-PTP), is used for down-regulation of virally ubiquitinated MHC class I.

Parkinson MD, Piper SC, Bright NA, Evans JL, Boname JM, Bowers K, Lehner PJ, Luzio JP. Parkinson MD, et al. Among authors: piper sc. Biochem J. 2015 Oct 1;471(1):79-88. doi: 10.1042/BJ20150336. Epub 2015 Jul 28. Biochem J. 2015. PMID: 26221024 Free PMC article.

6

Lysine-63-linked ubiquitination is required for endolysosomal degradation of class I molecules.

Duncan LM, Piper S, Dodd RB, Saville MK, Sanderson CM, Luzio JP, Lehner PJ. Duncan LM, et al. EMBO J. 2006 Apr 19;25(8):1635-45. doi: 10.1038/sj.emboj.7601056. Epub 2006 Apr 6. EMBO J. 2006. PMID: 16601694 Free PMC article.

7

Degradation of endocytosed epidermal growth factor and virally ubiquitinated major histocompatibility complex class I is independent of mammalian ESCRTII.

Bowers K, Piper SC, Edeling MA, Gray SR, Owen DJ, Lehner PJ, Luzio JP. Bowers K, et al. Among authors: piper sc. J Biol Chem. 2006 Feb 24;281(8):5094-105. doi: 10.1074/jbc.M508632200. Epub 2005 Dec 20. J Biol Chem. 2006. PMID: 16371348 Free article.

8

ESCRT proteins and the regulation of endocytic delivery to lysosomes.

Luzio JP, Piper SC, Bowers K, Parkinson MD, Lehner PJ, Bright NA. Luzio JP, et al. Among authors: piper sc. Biochem Soc Trans. 2009 Feb;37(Pt 1):178-80. doi: 10.1042/BST0370178. Biochem Soc Trans. 2009. PMID: 19143626

9

Proteomic analysis in primary T cells reveals IL-7 alters T cell receptor thresholding via CYTIP/cytohesin/LFA-1 localisation and activation.

Queiroz RML, Piper SC, Rees JS, Strickson S, Briend E, Low CP, Ferguson GJ, Lilley KS, Jackson AP, Finch DK. Queiroz RML, et al. Among authors: piper sc. Biochem J. 2022 Feb 11;479(3):225-243. doi: 10.1042/BCJ20210313. Biochem J. 2022. PMID: 35015072 Free PMC article.

10

The role of interleukin-1 and interleukin-18 in pro-inflammatory and anti-viral responses to rhinovirus in primary bronchial epithelial cells.

Piper SC, Ferguson J, Kay L, Parker LC, Sabroe I, Sleeman MA, Briend E, Finch DK. Piper SC, et al. PLoS One. 2013 May 28;8(5):e63365. doi: 10.1371/journal.pone.0063365. Print 2013. PLoS One. 2013. PMID: 23723976 Free PMC article.

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