Golde TE - Search Results

1

Peptide-based, irreversible inhibitors of gamma-secretase activity.

Piper SC, Amtul Z, Galiñanes-Garcia L, Howard VG, Ziani-Cherif C, McLendon C, Rochette MJ, Fauq A, Golde TE, Murphy MP. Piper SC, et al. Among authors: golde te. Biochem Biophys Res Commun. 2003 Jun 6;305(3):529-33. doi: 10.1016/s0006-291x(03)00828-3. Biochem Biophys Res Commun. 2003. PMID: 12763025

2

gamma-Secretase, evidence for multiple proteolytic activities and influence of membrane positioning of substrate on generation of amyloid beta peptides of varying length.

Murphy MP, Hickman LJ, Eckman CB, Uljon SN, Wang R, Golde TE. Murphy MP, et al. Among authors: golde te. J Biol Chem. 1999 Apr 23;274(17):11914-23. doi: 10.1074/jbc.274.17.11914. J Biol Chem. 1999. PMID: 10207012 Free article.

3

Presenilin 1 regulates pharmacologically distinct gamma -secretase activities. Implications for the role of presenilin in gamma -secretase cleavage.

Murphy MP, Uljon SN, Fraser PE, Fauq A, Lookingbill HA, Findlay KA, Smith TE, Lewis PA, McLendon DC, Wang R, Golde TE. Murphy MP, et al. Among authors: golde te. J Biol Chem. 2000 Aug 25;275(34):26277-84. doi: 10.1074/jbc.M002812200. J Biol Chem. 2000. PMID: 10816583 Free article.

4

Cell-free assays for gamma-secretase activity.

McLendon C, Xin T, Ziani-Cherif C, Murphy MP, Findlay KA, Lewis PA, Pinnix I, Sambamurti K, Wang R, Fauq A, Golde TE. McLendon C, et al. Among authors: golde te. FASEB J. 2000 Dec;14(15):2383-6. doi: 10.1096/fj.00-0286fje. FASEB J. 2000. PMID: 11024004

5

The presenilin 1 C92S mutation increases abeta 42 production.

Lewis PA, Perez-Tur J, Golde TE, Hardy J. Lewis PA, et al. Among authors: golde te. Biochem Biophys Res Commun. 2000 Oct 14;277(1):261-3. doi: 10.1006/bbrc.2000.3646. Biochem Biophys Res Commun. 2000. PMID: 11027672

6

A novel gamma -secretase assay based on detection of the putative C-terminal fragment-gamma of amyloid beta protein precursor.

Pinnix I, Musunuru U, Tun H, Sridharan A, Golde T, Eckman C, Ziani-Cherif C, Onstead L, Sambamurti K. Pinnix I, et al. J Biol Chem. 2001 Jan 5;276(1):481-7. doi: 10.1074/jbc.M005968200. J Biol Chem. 2001. PMID: 11035007 Free article.

7

An empirical model of gamma-secretase activity.

Murphy MP, Wang R, Fraser PE, Fauq A, Golde TE. Murphy MP, et al. Among authors: golde te. Ann N Y Acad Sci. 2000;920:233-40. doi: 10.1111/j.1749-6632.2000.tb06928.x. Ann N Y Acad Sci. 2000. PMID: 11193156

8

Presenilins as therapeutic targets for the treatment of Alzheimer's disease.

Golde TE, Younkin SG. Golde TE, et al. Trends Mol Med. 2001 Jun;7(6):264-9. doi: 10.1016/s1471-4914(01)02064-0. Trends Mol Med. 2001. PMID: 11378516 Review.

9

Expression of BRI-amyloid beta peptide fusion proteins: a novel method for specific high-level expression of amyloid beta peptides.

Lewis PA, Piper S, Baker M, Onstead L, Murphy MP, Hardy J, Wang R, McGowan E, Golde TE. Lewis PA, et al. Among authors: golde te. Biochim Biophys Acta. 2001 Jul 27;1537(1):58-62. doi: 10.1016/s0925-4439(01)00054-0. Biochim Biophys Acta. 2001. PMID: 11476963 Free article.

10

gamma -Secretase cleavage and nuclear localization of ErbB-4 receptor tyrosine kinase.

Ni CY, Murphy MP, Golde TE, Carpenter G. Ni CY, et al. Among authors: golde te. Science. 2001 Dec 7;294(5549):2179-81. doi: 10.1126/science.1065412. Epub 2001 Oct 25. Science. 2001. PMID: 11679632

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