Three-dimensional structure of a mutant HIV-1 protease displaying cross-resistance to all protease inhibitors in clinical trials.
Chen Z, Li Y, Schock HB, Hall D, Chen E, Kuo LC.
Chen Z, et al. Among authors: chen e.
J Biol Chem. 1995 Sep 15;270(37):21433-6. doi: 10.1074/jbc.270.37.21433.
J Biol Chem. 1995.
PMID: 7665551
Free article.
E., Deutsch, P. J., and Emini, E. A. (1995) Nature 374, 569-571). ...These structures are compared with those of the wild-type enzyme and its complex with MK639 (Chen, Z., Li, Y., Chen, E., Hall, D. L., Darke, P. L., Culberson, C., Shafer, J., a …
E., Deutsch, P. J., and Emini, E. A. (1995) Nature 374, 569-571). ...These structures are compared with those of the wild-type …