Flockhart DA - Search Results

1

Sequence diversity and functional characterization of the 5'-regulatory region of human CYP2C19.

Arefayene M, Skaar TC, Zhao X, Rae JM, Tanus-Santos JE, Brinkmann U, Brehm I, Salat U, Nguyen A, Desta Z, Flockhart DA. Arefayene M, et al. Among authors: flockhart da. Pharmacogenetics. 2003 Apr;13(4):199-206. doi: 10.1097/00008571-200304000-00004. Pharmacogenetics. 2003. PMID: 12668916

2

Identification of genetic variants in the human indoleamine 2,3-dioxygenase (IDO1) gene, which have altered enzyme activity.

Arefayene M, Philips S, Cao D, Mamidipalli S, Desta Z, Flockhart DA, Wilkes DS, Skaar TC. Arefayene M, et al. Among authors: flockhart da. Pharmacogenet Genomics. 2009 Jun;19(6):464-76. doi: 10.1097/fpc.0b013e32832c005a. Pharmacogenet Genomics. 2009. PMID: 19514129

3

Effects of endothelial nitric oxide synthase gene polymorphisms on platelet function, nitric oxide release, and interactions with estradiol.

Tanus-Santos JE, Desai M, Deak LR, Pezzullo JC, Abernethy DR, Flockhart DA, Freedman JE. Tanus-Santos JE, et al. Among authors: flockhart da. Pharmacogenetics. 2002 Jul;12(5):407-13. doi: 10.1097/00008571-200207000-00008. Pharmacogenetics. 2002. PMID: 12142730

4

Endoxifen (4-hydroxy-N-desmethyl-tamoxifen) has anti-estrogenic effects in breast cancer cells with potency similar to 4-hydroxy-tamoxifen.

Lim YC, Desta Z, Flockhart DA, Skaar TC. Lim YC, et al. Among authors: flockhart da. Cancer Chemother Pharmacol. 2005 May;55(5):471-8. doi: 10.1007/s00280-004-0926-7. Epub 2005 Feb 1. Cancer Chemother Pharmacol. 2005. PMID: 15685451

5

Endoxifen, a secondary metabolite of tamoxifen, and 4-OH-tamoxifen induce similar changes in global gene expression patterns in MCF-7 breast cancer cells.

Lim YC, Li L, Desta Z, Zhao Q, Rae JM, Flockhart DA, Skaar TC. Lim YC, et al. Among authors: flockhart da. J Pharmacol Exp Ther. 2006 Aug;318(2):503-12. doi: 10.1124/jpet.105.100511. Epub 2006 May 11. J Pharmacol Exp Ther. 2006. PMID: 16690721

6

Differential quantification of CYP2D6 gene copy number by four different quantitative real-time PCR assays.

Ramamoorthy A, Flockhart DA, Hosono N, Kubo M, Nakamura Y, Skaar TC. Ramamoorthy A, et al. Among authors: flockhart da. Pharmacogenet Genomics. 2010 Jul;20(7):451-4. doi: 10.1097/FPC.0b013e32833a1083. Pharmacogenet Genomics. 2010. PMID: 20421845 Free PMC article.

7

Functional characterization of a genetic polymorphism in the promoter of the ESR2 gene.

Philips S, Richter A, Oesterreich S, Rae JM, Flockhart DA, Perumal NB, Skaar TC. Philips S, et al. Among authors: flockhart da. Horm Cancer. 2012 Apr;3(1-2):37-43. doi: 10.1007/s12672-011-0086-2. Horm Cancer. 2012. PMID: 21979797 Free PMC article.

8

Associations between genetic variants and the effect of letrozole and exemestane on bone mass and bone turnover.

Oesterreich S, Henry NL, Kidwell KM, Van Poznak CH, Skaar TC, Dantzer J, Li L, Hangartner TN, Peacock M, Nguyen AT, Rae JM, Desta Z, Philips S, Storniolo AM, Stearns V, Hayes DF, Flockhart DA. Oesterreich S, et al. Among authors: flockhart da. Breast Cancer Res Treat. 2015 Nov;154(2):263-73. doi: 10.1007/s10549-015-3608-8. Epub 2015 Nov 4. Breast Cancer Res Treat. 2015. PMID: 26536870 Free PMC article.

9

PharmGKB summary: tamoxifen pathway, pharmacokinetics.

Klein DJ, Thorn CF, Desta Z, Flockhart DA, Altman RB, Klein TE. Klein DJ, et al. Among authors: flockhart da. Pharmacogenet Genomics. 2013 Nov;23(11):643-7. doi: 10.1097/FPC.0b013e3283656bc1. Pharmacogenet Genomics. 2013. PMID: 23962908 Free PMC article. Review. No abstract available.

10

Implications of cytochrome P450 interactions when prescribing medication for hypertension.

Flockhart DA, Tanus-Santos JE. Flockhart DA, et al. Arch Intern Med. 2002 Feb 25;162(4):405-12. doi: 10.1001/archinte.162.4.405. Arch Intern Med. 2002. PMID: 11863472 Review.

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