Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search Page

Filters

My NCBI Filters

Text availability

Article attribute

Article type

Publication date

Search Results

26 results

Filters applied: . Clear all
Results are displayed in a computed author sort order. The Results By Year timeline is not available.
Page 1
Synthesis and biological evaluation of non-peptidic cyclophilin ligands.
Wu YQ, Belyakov S, Choi C, Limburg D, Thomas IV BE, Vaal M, Wei L, Wilkinson DE, Holmes A, Fuller M, McCormick J, Connolly M, Moeller T, Steiner J, Hamilton GS. Wu YQ, et al. Among authors: limburg d. J Med Chem. 2003 Mar 27;46(7):1112-5. doi: 10.1021/jm020409u. J Med Chem. 2003. PMID: 12646018
Synthesis of N-glyoxyl prolyl and pipecolyl amides and thioesters and evaluation of their in vitro and in vivo nerve regenerative effects.
Hamilton GS, Wu YQ, Limburg DC, Wilkinson DE, Vaal MJ, Li JH, Thomas C, Huang W, Sauer H, Ross DT, Soni R, Chen Y, Guo H, Howorth P, Valentine H, Liang S, Spicer D, Fuller M, Steiner JP. Hamilton GS, et al. Among authors: limburg dc. J Med Chem. 2002 Aug 1;45(16):3549-57. doi: 10.1021/jm010556c. J Med Chem. 2002. PMID: 12139466
Synthesis and evaluation of chiral bicyclic proline FKBP12 ligands.
Limburg DC, Thomas BE 4th, Li JH, Fuller M, Spicer D, Chen Y, Guo H, Steiner JP, Hamilton GS, Wu YQ. Limburg DC, et al. Bioorg Med Chem Lett. 2003 Nov 3;13(21):3867-70. doi: 10.1016/s0960-894x(03)00758-3. Bioorg Med Chem Lett. 2003. PMID: 14552797
Synthesis, molecular modeling and biological evaluation of aza-proline and aza-pipecolic derivatives as FKBP12 ligands and their in vivo neuroprotective effects.
Wilkinson DE, Thomas BE 4th, Limburg DC, Holmes A, Sauer H, Ross DT, Soni R, Chen Y, Guo H, Howorth P, Valentine H, Spicer D, Fuller M, Steiner JP, Hamilton GS, Wu YQ. Wilkinson DE, et al. Among authors: limburg dc. Bioorg Med Chem. 2003 Nov 3;11(22):4815-25. doi: 10.1016/s0968-0896(03)00478-4. Bioorg Med Chem. 2003. PMID: 14556798
Synthesis of ketone analogues of prolyl and pipecolyl ester FKBP12 ligands.
Wu YQ, Wilkinson DE, Limburg D, Li JH, Sauer H, Ross D, Liang S, Spicer D, Valentine H, Fuller M, Guo H, Howorth P, Soni R, Chen Y, Steiner JP, Hamilton GS. Wu YQ, et al. Among authors: limburg d. J Med Chem. 2002 Aug 1;45(16):3558-68. doi: 10.1021/jm0200456. J Med Chem. 2002. PMID: 12139467
Design and optimization of a series of 4-(3-azabicyclo[3.1.0]hexan-3-yl)pyrimidin-2-amines: Dual inhibitors of TYK2 and JAK1.
Fensome A, Ambler CM, Arnold E, Banker ME, Clark JD, Dowty ME, Efremov IV, Flick A, Gerstenberger BS, Gifford RS, Gopalsamy A, Hegen M, Jussif J, Limburg DC, Lin TH, Pierce BS, Sharma R, Trujillo JI, Vajdos FF, Vincent F, Wan ZK, Xing L, Yang X, Yang X. Fensome A, et al. Among authors: limburg dc. Bioorg Med Chem. 2020 May 15;28(10):115481. doi: 10.1016/j.bmc.2020.115481. Epub 2020 Mar 31. Bioorg Med Chem. 2020. PMID: 32253095
Dual Inhibition of TYK2 and JAK1 for the Treatment of Autoimmune Diseases: Discovery of (( S)-2,2-Difluorocyclopropyl)((1 R,5 S)-3-(2-((1-methyl-1 H-pyrazol-4-yl)amino)pyrimidin-4-yl)-3,8-diazabicyclo[3.2.1]octan-8-yl)methanone (PF-06700841).
Fensome A, Ambler CM, Arnold E, Banker ME, Brown MF, Chrencik J, Clark JD, Dowty ME, Efremov IV, Flick A, Gerstenberger BS, Gopalsamy A, Hayward MM, Hegen M, Hollingshead BD, Jussif J, Knafels JD, Limburg DC, Lin D, Lin TH, Pierce BS, Saiah E, Sharma R, Symanowicz PT, Telliez JB, Trujillo JI, Vajdos FF, Vincent F, Wan ZK, Xing L, Yang X, Yang X, Zhang L. Fensome A, et al. Among authors: limburg dc. J Med Chem. 2018 Oct 11;61(19):8597-8612. doi: 10.1021/acs.jmedchem.8b00917. Epub 2018 Aug 16. J Med Chem. 2018. PMID: 30113844
26 results