Okamoto H - Search Results

1

Recent advances in the Okamoto model: the CD38-cyclic ADP-ribose signal system and the regenerating gene protein (Reg)-Reg receptor system in beta-cells.

Okamoto H, Takasawa S. Okamoto H, et al. Diabetes. 2002 Dec;51 Suppl 3:S462-73. doi: 10.2337/diabetes.51.2007.s462. Diabetes. 2002. PMID: 12475791 Review.

2

Pancreatic beta-cell death, regeneration and insulin secretion: roles of poly(ADP-ribose) polymerase and cyclic ADP-ribose.

Takasawa S, Okamoto H. Takasawa S, et al. Among authors: okamoto h. Int J Exp Diabetes Res. 2002 Apr-Jun;3(2):79-96. doi: 10.1080/15604280214485. Int J Exp Diabetes Res. 2002. PMID: 11991201 Free PMC article. Review.

3

Production and characterization of Reg knockout mice: reduced proliferation of pancreatic beta-cells in Reg knockout mice.

Unno M, Nata K, Noguchi N, Narushima Y, Akiyama T, Ikeda T, Nakagawa K, Takasawa S, Okamoto H. Unno M, et al. Among authors: okamoto h. Diabetes. 2002 Dec;51 Suppl 3:S478-83. doi: 10.2337/diabetes.51.2007.s478. Diabetes. 2002. PMID: 12475793

4

Deficit of CD38/cyclic ADP-ribose is differentially compensated in hearts by gender.

Takahashi J, Kagaya Y, Kato I, Ohta J, Isoyama S, Miura M, Sugai Y, Hirose M, Wakayama Y, Ninomiya M, Watanabe J, Takasawa S, Okamoto H, Shirato K. Takahashi J, et al. Among authors: okamoto h. Biochem Biophys Res Commun. 2003 Dec 12;312(2):434-40. doi: 10.1016/j.bbrc.2003.10.143. Biochem Biophys Res Commun. 2003. PMID: 14637156

5

CD38 gene disruption inhibits the contraction induced by alpha-adrenoceptor stimulation in mouse aorta.

Mitsui-Saito M, Kato I, Takasawa S, Okamoto H, Yanagisawa T. Mitsui-Saito M, et al. Among authors: okamoto h. J Vet Med Sci. 2003 Dec;65(12):1325-30. doi: 10.1292/jvms.65.1325. J Vet Med Sci. 2003. PMID: 14709821

6

Overexpression of human CD38/ADP-ribosyl cyclase enhances acetylcholine-induced Ca2+ signalling in rodent NG108-15 neuroblastoma cells.

Higashida H, Bowden SE, Yokoyama S, Salmina A, Hashii M, Hoshi N, Zhang JS, Knijnik R, Noda M, Zhong ZG, Jin D, Higashida K, Takeda H, Akita T, Kuba K, Yamagishi S, Shimizu N, Takasawa S, Okamoto H, Robbins J. Higashida H, et al. Among authors: okamoto h. Neurosci Res. 2007 Mar;57(3):339-46. doi: 10.1016/j.neures.2006.11.008. Epub 2006 Dec 14. Neurosci Res. 2007. PMID: 17173996

7

Generation of nicotinic acid adenine dinucleotide phosphate and cyclic ADP-ribose by glucagon-like peptide-1 evokes Ca2+ signal that is essential for insulin secretion in mouse pancreatic islets.

Kim BJ, Park KH, Yim CY, Takasawa S, Okamoto H, Im MJ, Kim UH. Kim BJ, et al. Among authors: okamoto h. Diabetes. 2008 Apr;57(4):868-78. doi: 10.2337/db07-0443. Epub 2008 Jan 9. Diabetes. 2008. PMID: 18184929

8

Recent advances in physiological and pathological significance of NAD+ metabolites: roles of poly(ADP-ribose) and cyclic ADP-ribose in insulin secretion and diabetogenesis.

Okamoto H, Takasawa S. Okamoto H, et al. Nutr Res Rev. 2003 Dec;16(2):253-66. doi: 10.1079/NRR200362. Nutr Res Rev. 2003. PMID: 19087393

9

Identification of a major enzyme for the synthesis and hydrolysis of cyclic ADP-ribose in amphibian cells and evolutional conservation of the enzyme from human to invertebrate.

Ikeda T, Takasawa S, Noguchi N, Nata K, Yamauchi A, Takahashi I, Yoshikawa T, Sugawara A, Yonekura H, Okamoto H. Ikeda T, et al. Among authors: okamoto h. Mol Cell Biochem. 2012 Jul;366(1-2):69-80. doi: 10.1007/s11010-012-1284-0. Epub 2012 Mar 16. Mol Cell Biochem. 2012. PMID: 22422046

10

Okamoto model for necrosis and its expansions, CD38-cyclic ADP-ribose signal system for intracellular Ca²⁺ mobilization and Reg (Regenerating gene protein)-Reg receptor system for cell regeneration.

Okamoto H, Takasawa S. Okamoto H, et al. Proc Jpn Acad Ser B Phys Biol Sci. 2021;97(8):423-461. doi: 10.2183/pjab.97.022. Proc Jpn Acad Ser B Phys Biol Sci. 2021. PMID: 34629354 Free PMC article.

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