Sugi NH - Search Results

1

Profiling novel sulfonamide antitumor agents with cell-based phenotypic screens and array-based gene expression analysis.

Yokoi A, Kuromitsu J, Kawai T, Nagasu T, Sugi NH, Yoshimatsu K, Yoshino H, Owa T. Yokoi A, et al. Among authors: sugi nh. Mol Cancer Ther. 2002 Feb;1(4):275-86. Mol Cancer Ther. 2002. PMID: 12467223

2

Discovery of novel antitumor sulfonamides targeting G1 phase of the cell cycle.

Owa T, Yoshino H, Okauchi T, Yoshimatsu K, Ozawa Y, Sugi NH, Nagasu T, Koyanagi N, Kitoh K. Owa T, et al. Among authors: sugi nh. J Med Chem. 1999 Sep 23;42(19):3789-99. doi: 10.1021/jm9902638. J Med Chem. 1999. PMID: 10508428

3

A focused compound library of novel N-(7-indolyl)benzenesulfonamides for the discovery of potent cell cycle inhibitors.

Owa T, Okauchi T, Yoshimatsu K, Sugi NH, Ozawa Y, Nagasu T, Koyanagi N, Okabe T, Kitoh K, Yoshino H. Owa T, et al. Among authors: sugi nh. Bioorg Med Chem Lett. 2000 Jun 5;10(11):1223-6. doi: 10.1016/s0960-894x(00)00219-5. Bioorg Med Chem Lett. 2000. PMID: 10866386

4

E7070, a novel sulphonamide agent with potent antitumour activity in vitro and in vivo.

Ozawa Y, Sugi NH, Nagasu T, Owa T, Watanabe T, Koyanagi N, Yoshino H, Kitoh K, Yoshimatsu K. Ozawa Y, et al. Among authors: sugi nh. Eur J Cancer. 2001 Nov;37(17):2275-82. doi: 10.1016/s0959-8049(01)00275-1. Eur J Cancer. 2001. PMID: 11677118

5

Sulfonamide derivative, E7820, is a unique angiogenesis inhibitor suppressing an expression of integrin alpha2 subunit on endothelium.

Funahashi Y, Sugi NH, Semba T, Yamamoto Y, Hamaoka S, Tsukahara-Tamai N, Ozawa Y, Tsuruoka A, Nara K, Takahashi K, Okabe T, Kamata J, Owa T, Ueda N, Haneda T, Yonaga M, Yoshimatsu K, Wakabayashi T. Funahashi Y, et al. Among authors: sugi nh. Cancer Res. 2002 Nov 1;62(21):6116-23. Cancer Res. 2002. PMID: 12414636

6

An angiogenesis inhibitor E7820 shows broad-spectrum tumor growth inhibition in a xenograft model: possible value of integrin alpha2 on platelets as a biological marker.

Semba T, Funahashi Y, Ono N, Yamamoto Y, Sugi NH, Asada M, Yoshimatsu K, Wakabayashi T. Semba T, et al. Among authors: sugi nh. Clin Cancer Res. 2004 Feb 15;10(4):1430-8. doi: 10.1158/1078-0432.ccr-0109-03. Clin Cancer Res. 2004. PMID: 14977846

7

Biological validation that SF3b is a target of the antitumor macrolide pladienolide.

Yokoi A, Kotake Y, Takahashi K, Kadowaki T, Matsumoto Y, Minoshima Y, Sugi NH, Sagane K, Hamaguchi M, Iwata M, Mizui Y. Yokoi A, et al. Among authors: sugi nh. FEBS J. 2011 Dec;278(24):4870-80. doi: 10.1111/j.1742-4658.2011.08387.x. Epub 2011 Oct 31. FEBS J. 2011. PMID: 21981285 Free article.

8

Antitumor activities of the targeted multi-tyrosine kinase inhibitor lenvatinib (E7080) against RET gene fusion-driven tumor models.

Okamoto K, Kodama K, Takase K, Sugi NH, Yamamoto Y, Iwata M, Tsuruoka A. Okamoto K, et al. Among authors: sugi nh. Cancer Lett. 2013 Oct 28;340(1):97-103. doi: 10.1016/j.canlet.2013.07.007. Epub 2013 Jul 12. Cancer Lett. 2013. PMID: 23856031 Free article.

9

E7090, a Novel Selective Inhibitor of Fibroblast Growth Factor Receptors, Displays Potent Antitumor Activity and Prolongs Survival in Preclinical Models.

Watanabe Miyano S, Yamamoto Y, Kodama K, Miyajima Y, Mikamoto M, Nakagawa T, Kuramochi H, Funasaka S, Nagao S, Sugi NH, Okamoto K, Minoshima Y, Nakatani Y, Karoji Y, Ohashi I, Yamane Y, Okada T, Matsushima T, Matsui J, Iwata M, Uenaka T, Tsuruoka A. Watanabe Miyano S, et al. Among authors: sugi nh. Mol Cancer Ther. 2016 Nov;15(11):2630-2639. doi: 10.1158/1535-7163.MCT-16-0261. Epub 2016 Aug 17. Mol Cancer Ther. 2016. PMID: 27535969

10

Selective degradation of splicing factor CAPERα by anticancer sulfonamides.

Uehara T, Minoshima Y, Sagane K, Sugi NH, Mitsuhashi KO, Yamamoto N, Kamiyama H, Takahashi K, Kotake Y, Uesugi M, Yokoi A, Inoue A, Yoshida T, Mabuchi M, Tanaka A, Owa T. Uehara T, et al. Among authors: sugi nh. Nat Chem Biol. 2017 Jun;13(6):675-680. doi: 10.1038/nchembio.2363. Epub 2017 Apr 24. Nat Chem Biol. 2017. PMID: 28437394

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