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Interferon-alpha, but not the ABL-kinase inhibitor imatinib (STI571), induces expression of myeloblastin and a specific T-cell response in chronic myeloid leukemia.
Burchert A, Wölfl S, Schmidt M, Brendel C, Denecke B, Cai D, Odyvanova L, Lahaye T, Müller MC, Berg T, Gschaidmeier H, Wittig B, Hehlmann R, Hochhaus A, Neubauer A. Burchert A, et al. Among authors: hehlmann r. Blood. 2003 Jan 1;101(1):259-64. doi: 10.1182/blood-2002-02-0659. Epub 2002 Jun 28. Blood. 2003. PMID: 12393722 Free article.
[Drug therapy of chronic myeloid leukemia].
Hochhaus A, Berger U, Reiter A, Lahaye T, Kreil S, Hehlmann R. Hochhaus A, et al. Among authors: hehlmann r. Med Klin (Munich). 2002 Jan 15;97 Suppl 1:7-15. Med Klin (Munich). 2002. PMID: 11831070 German.
Telomere length in peripheral blood granulocytes reflects response to treatment with imatinib in patients with chronic myeloid leukemia.
Brümmendorf TH, Ersöz I, Hartmann U, Bartolovic K, Balabanov S, Wahl A, Paschka P, Kreil S, Lahaye T, Berger U, Gschaidmeier H, Bokemeyer C, Hehlmann R, Dietz K, Lansdorp PM, Kanz L, Hochhaus A. Brümmendorf TH, et al. Among authors: hehlmann r. Blood. 2003 Jan 1;101(1):375-6. doi: 10.1182/blood-2002-08-2557. Blood. 2003. PMID: 12485943 Free article. No abstract available.
Normalization of previously shortened telomere length under treatment with imatinib argues against a preexisting telomere length deficit in normal hematopoietic stem cells from patients with chronic myeloid leukemia.
Brummendorf TH, Ersoz I, Hartmann U, Balabanov S, Wolke H, Paschka P, Lahaye T, Berner B, Bartolovic K, Kreil S, Berger U, Gschaidmeier H, Bokemeyer C, Hehlmann R, Dietz K, Lansdorp PM, Kanz L, Hochhaus A. Brummendorf TH, et al. Among authors: hehlmann r. Ann N Y Acad Sci. 2003 May;996:26-38. doi: 10.1111/j.1749-6632.2003.tb03229.x. Ann N Y Acad Sci. 2003. PMID: 12799279 Clinical Trial.
Pegylated liposomal doxorubicin and mitomycin C in combination with infusional 5-fluorouracil and sodium folinic acid in the treatment of advanced gastric cancer: results of a phase II trial.
Gnad-Vogt SU, Hofheinz RD, Saussele S, Kreil S, Willer A, Willeke F, Pilz L, Hehlmann R, Hochhaus A. Gnad-Vogt SU, et al. Among authors: hehlmann r. Anticancer Drugs. 2005 Apr;16(4):435-40. doi: 10.1097/00001813-200504000-00010. Anticancer Drugs. 2005. PMID: 15746580 Clinical Trial.
The t(8;9)(p22;p24) is a recurrent abnormality in chronic and acute leukemia that fuses PCM1 to JAK2.
Reiter A, Walz C, Watmore A, Schoch C, Blau I, Schlegelberger B, Berger U, Telford N, Aruliah S, Yin JA, Vanstraelen D, Barker HF, Taylor PC, O'Driscoll A, Benedetti F, Rudolph C, Kolb HJ, Hochhaus A, Hehlmann R, Chase A, Cross NC. Reiter A, et al. Among authors: hehlmann r. Cancer Res. 2005 Apr 1;65(7):2662-7. doi: 10.1158/0008-5472.CAN-04-4263. Cancer Res. 2005. PMID: 15805263 Free article.
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