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Page 1
Serpins: finely balanced conformational traps.
Pike RN, Bottomley SP, Irving JA, Bird PI, Whisstock JC. Pike RN, et al. Among authors: bird pi. IUBMB Life. 2002 Jul;54(1):1-7. doi: 10.1080/15216540213825. IUBMB Life. 2002. PMID: 12387568 Free article. Review.
The high resolution crystal structure of the human tumor suppressor maspin reveals a novel conformational switch in the G-helix.
Law RH, Irving JA, Buckle AM, Ruzyla K, Buzza M, Bashtannyk-Puhalovich TA, Beddoe TC, Nguyen K, Worrall DM, Bottomley SP, Bird PI, Rossjohn J, Whisstock JC. Law RH, et al. Among authors: bird pi. J Biol Chem. 2005 Jun 10;280(23):22356-64. doi: 10.1074/jbc.M412043200. Epub 2005 Mar 10. J Biol Chem. 2005. PMID: 15760906 Free article.
Mechanisms of serpin dysfunction in disease.
Kaiserman D, Whisstock JC, Bird PI. Kaiserman D, et al. Among authors: bird pi. Expert Rev Mol Med. 2006 Dec 11;8(31):1-19. doi: 10.1017/S1462399406000184. Expert Rev Mol Med. 2006. PMID: 17156576 Review.
Elucidation of the substrate specificity of the MASP-2 protease of the lectin complement pathway and identification of the enzyme as a major physiological target of the serpin, C1-inhibitor.
Kerr FK, Thomas AR, Wijeyewickrema LC, Whisstock JC, Boyd SE, Kaiserman D, Matthews AY, Bird PI, Thielens NM, Rossi V, Pike RN. Kerr FK, et al. Among authors: bird pi. Mol Immunol. 2008 Feb;45(3):670-7. doi: 10.1016/j.molimm.2007.07.008. Epub 2007 Aug 20. Mol Immunol. 2008. PMID: 17709141
A common fold mediates vertebrate defense and bacterial attack.
Rosado CJ, Buckle AM, Law RH, Butcher RE, Kan WT, Bird CH, Ung K, Browne KA, Baran K, Bashtannyk-Puhalovich TA, Faux NG, Wong W, Porter CJ, Pike RN, Ellisdon AM, Pearce MC, Bottomley SP, Emsley J, Smith AI, Rossjohn J, Hartland EL, Voskoboinik I, Trapani JA, Bird PI, Dunstone MA, Whisstock JC. Rosado CJ, et al. Among authors: bird pi, bird ch. Science. 2007 Sep 14;317(5844):1548-51. doi: 10.1126/science.1144706. Epub 2007 Aug 23. Science. 2007. PMID: 17717151
SerpinB6 is an inhibitor of kallikrein-8 in keratinocytes.
Scott FL, Sun J, Whisstock JC, Kato K, Bird PI. Scott FL, et al. Among authors: bird pi. J Biochem. 2007 Oct;142(4):435-42. doi: 10.1093/jb/mvm156. Epub 2007 Aug 30. J Biochem. 2007. PMID: 17761692
202 results