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Serum creatinine levels correlate with plasma amyloid Beta protein.
Arvanitakis Z, Lucas JA, Younkin LH, Younkin SG, Graff-Radford NR. Arvanitakis Z, et al. Among authors: younkin lh, younkin sg. Alzheimer Dis Assoc Disord. 2002 Jul-Sep;16(3):187-90. doi: 10.1097/00002093-200207000-00009. Alzheimer Dis Assoc Disord. 2002. PMID: 12218650
Elevated amyloid beta protein (Abeta42) and late onset Alzheimer's disease are associated with single nucleotide polymorphisms in the urokinase-type plasminogen activator gene.
Ertekin-Taner N, Ronald J, Feuk L, Prince J, Tucker M, Younkin L, Hella M, Jain S, Hackett A, Scanlin L, Kelly J, Kihiko-Ehman M, Neltner M, Hersh L, Kindy M, Markesbery W, Hutton M, de Andrade M, Petersen RC, Graff-Radford N, Estus S, Brookes AJ, Younkin SG. Ertekin-Taner N, et al. Hum Mol Genet. 2005 Feb 1;14(3):447-60. doi: 10.1093/hmg/ddi041. Epub 2004 Dec 22. Hum Mol Genet. 2005. PMID: 15615772
Plasma amyloid-β and risk of Alzheimer's disease in the Framingham Heart Study.
Chouraki V, Beiser A, Younkin L, Preis SR, Weinstein G, Hansson O, Skoog I, Lambert JC, Au R, Launer L, Wolf PA, Younkin S, Seshadri S. Chouraki V, et al. Alzheimers Dement. 2015 Mar;11(3):249-57.e1. doi: 10.1016/j.jalz.2014.07.001. Epub 2014 Sep 10. Alzheimers Dement. 2015. PMID: 25217292 Free PMC article.
Mutant presenilins specifically elevate the levels of the 42 residue beta-amyloid peptide in vivo: evidence for augmentation of a 42-specific gamma secretase.
Jankowsky JL, Fadale DJ, Anderson J, Xu GM, Gonzales V, Jenkins NA, Copeland NG, Lee MK, Younkin LH, Wagner SL, Younkin SG, Borchelt DR. Jankowsky JL, et al. Among authors: younkin lh, younkin sg. Hum Mol Genet. 2004 Jan 15;13(2):159-70. doi: 10.1093/hmg/ddh019. Epub 2003 Nov 25. Hum Mol Genet. 2004. PMID: 14645205
Dimeric amyloid beta protein rapidly accumulates in lipid rafts followed by apolipoprotein E and phosphorylated tau accumulation in the Tg2576 mouse model of Alzheimer's disease.
Kawarabayashi T, Shoji M, Younkin LH, Wen-Lang L, Dickson DW, Murakami T, Matsubara E, Abe K, Ashe KH, Younkin SG. Kawarabayashi T, et al. Among authors: younkin lh, younkin sg. J Neurosci. 2004 Apr 14;24(15):3801-9. doi: 10.1523/JNEUROSCI.5543-03.2004. J Neurosci. 2004. PMID: 15084661 Free PMC article.
75 results