Meijer L - Search Results

1

Purine-based inhibitors of inositol-1,4,5-trisphosphate-3-kinase.

Chang YT, Choi G, Bae YS, Burdett M, Moon HS, Lee JW, Gray NS, Schultz PG, Meijer L, Chung SK, Choi KY, Suh PG, Ryu SH. Chang YT, et al. Among authors: meijer l. Chembiochem. 2002 Sep 2;3(9):897-901. doi: 10.1002/1439-7633(20020902)3:9<897::AID-CBIC897>3.0.CO;2-B. Chembiochem. 2002. PMID: 12210991 No abstract available.

2

Synthesis and application of functionally diverse 2,6,9-trisubstituted purine libraries as CDK inhibitors.

Chang YT, Gray NS, Rosania GR, Sutherlin DP, Kwon S, Norman TC, Sarohia R, Leost M, Meijer L, Schultz PG. Chang YT, et al. Among authors: meijer l. Chem Biol. 1999 Jun;6(6):361-75. doi: 10.1016/S1074-5521(99)80048-9. Chem Biol. 1999. PMID: 10375538

3

Synthesis and target identification of hymenialdisine analogs.

Wan Y, Hur W, Cho CY, Liu Y, Adrian FJ, Lozach O, Bach S, Mayer T, Fabbro D, Meijer L, Gray NS. Wan Y, et al. Among authors: meijer l. Chem Biol. 2004 Feb;11(2):247-59. doi: 10.1016/j.chembiol.2004.01.015. Chem Biol. 2004. PMID: 15123286

4

Structure-activity relationships and inhibitory effects of various purine derivatives on the in vitro growth of Plasmodium falciparum.

Harmse L, van Zyl R, Gray N, Schultz P, Leclerc S, Meijer L, Doerig C, Havlik I. Harmse L, et al. Among authors: meijer l. Biochem Pharmacol. 2001 Aug 1;62(3):341-8. doi: 10.1016/s0006-2952(01)00644-x. Biochem Pharmacol. 2001. PMID: 11434907

5

ATP-site directed inhibitors of cyclin-dependent kinases.

Gray N, Détivaud L, Doerig C, Meijer L. Gray N, et al. Among authors: meijer l. Curr Med Chem. 1999 Sep;6(9):859-75. Curr Med Chem. 1999. PMID: 10495356 Review.

6

Intracellular targets of cyclin-dependent kinase inhibitors: identification by affinity chromatography using immobilised inhibitors.

Knockaert M, Gray N, Damiens E, Chang YT, Grellier P, Grant K, Fergusson D, Mottram J, Soete M, Dubremetz JF, Le Roch K, Doerig C, Schultz P, Meijer L. Knockaert M, et al. Among authors: meijer l. Chem Biol. 2000 Jun;7(6):411-22. doi: 10.1016/s1074-5521(00)00124-1. Chem Biol. 2000. PMID: 10873834

7

Exploiting chemical libraries, structure, and genomics in the search for kinase inhibitors.

Gray NS, Wodicka L, Thunnissen AM, Norman TC, Kwon S, Espinoza FH, Morgan DO, Barnes G, LeClerc S, Meijer L, Kim SH, Lockhart DJ, Schultz PG. Gray NS, et al. Among authors: meijer l. Science. 1998 Jul 24;281(5376):533-8. doi: 10.1126/science.281.5376.533. Science. 1998. PMID: 9677190 Free article.

8

Pharmacological cyclin-dependent kinase inhibitors inhibit replication of wild-type and drug-resistant strains of herpes simplex virus and human immunodeficiency virus type 1 by targeting cellular, not viral, proteins.

Schang LM, Bantly A, Knockaert M, Shaheen F, Meijer L, Malim MH, Gray NS, Schaffer PA. Schang LM, et al. Among authors: meijer l. J Virol. 2002 Aug;76(15):7874-82. doi: 10.1128/jvi.76.15.7874-7882.2002. J Virol. 2002. PMID: 12097601 Free PMC article.

9

p42/p44 MAPKs are intracellular targets of the CDK inhibitor purvalanol.

Knockaert M, Lenormand P, Gray N, Schultz P, Pouysségur J, Meijer L. Knockaert M, et al. Among authors: meijer l. Oncogene. 2002 Sep 19;21(42):6413-24. doi: 10.1038/sj.onc.1205908. Oncogene. 2002. PMID: 12226745

10

Structure-aided optimization of kinase inhibitors derived from alsterpaullone.

Kunick C, Zeng Z, Gussio R, Zaharevitz D, Leost M, Totzke F, Schächtele C, Kubbutat MH, Meijer L, Lemcke T. Kunick C, et al. Among authors: meijer l. Chembiochem. 2005 Mar;6(3):541-9. doi: 10.1002/cbic.200400099. Chembiochem. 2005. PMID: 15696597

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