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Establishment of a binding assay for protein kinase C isozymes using synthetic C1 peptides and development of new medicinal leads with protein kinase C isozyme and C1 domain selectivity.
Irie K, Nakahara A, Nakagawa Y, Ohigashi H, Shindo M, Fukuda H, Konishi H, Kikkawa U, Kashiwagi K, Saito N. Irie K, et al. Among authors: shindo m. Pharmacol Ther. 2002 Feb-Mar;93(2-3):271-81. doi: 10.1016/s0163-7258(02)00196-1. Pharmacol Ther. 2002. PMID: 12191619 Review.
Toward the identification of selective modulators of protein kinase C (PKC) isozymes: establishment of a binding assay for PKC isozymes using synthetic C1 peptide receptors and identification of the critical residues involved in the phorbol ester binding.
Shindo M, Irie K, Nakahara A, Ohigashi H, Konishi H, Kikkawa U, Fukuda H, Wender PA. Shindo M, et al. Bioorg Med Chem. 2001 Aug;9(8):2073-81. doi: 10.1016/s0968-0896(01)00100-6. Bioorg Med Chem. 2001. PMID: 11504643
Neurotoxicity and physicochemical properties of Abeta mutant peptides from cerebral amyloid angiopathy: implication for the pathogenesis of cerebral amyloid angiopathy and Alzheimer's disease.
Murakami K, Irie K, Morimoto A, Ohigashi H, Shindo M, Nagao M, Shimizu T, Shirasawa T. Murakami K, et al. Among authors: shindo m. J Biol Chem. 2003 Nov 14;278(46):46179-87. doi: 10.1074/jbc.M301874200. Epub 2003 Aug 27. J Biol Chem. 2003. PMID: 12944403 Free article.
790 results