Konishi H - Search Results

1

Establishment of a binding assay for protein kinase C isozymes using synthetic C1 peptides and development of new medicinal leads with protein kinase C isozyme and C1 domain selectivity.

Irie K, Nakahara A, Nakagawa Y, Ohigashi H, Shindo M, Fukuda H, Konishi H, Kikkawa U, Kashiwagi K, Saito N. Irie K, et al. Among authors: konishi h. Pharmacol Ther. 2002 Feb-Mar;93(2-3):271-81. doi: 10.1016/s0163-7258(02)00196-1. Pharmacol Ther. 2002. PMID: 12191619 Review.

2

Synthesis and phorbol ester-binding studies of the individual cysteine-rich motifs of protein kinase D.

Irie K, Nakahara A, Ohigashi H, Fukuda H, Wender PA, Konishi H, Kikkawa U. Irie K, et al. Among authors: konishi h. Bioorg Med Chem Lett. 1999 Sep 6;9(17):2487-90. doi: 10.1016/s0960-894x(99)00413-8. Bioorg Med Chem Lett. 1999. PMID: 10498194

3

Toward the identification of selective modulators of protein kinase C (PKC) isozymes: establishment of a binding assay for PKC isozymes using synthetic C1 peptide receptors and identification of the critical residues involved in the phorbol ester binding.

Shindo M, Irie K, Nakahara A, Ohigashi H, Konishi H, Kikkawa U, Fukuda H, Wender PA. Shindo M, et al. Among authors: konishi h. Bioorg Med Chem. 2001 Aug;9(8):2073-81. doi: 10.1016/s0968-0896(01)00100-6. Bioorg Med Chem. 2001. PMID: 11504643

4

The pleckstrin homology domain of RAC protein kinase associates with the regulatory domain of protein kinase C zeta.

Konishi H, Kuroda S, Kikkawa U. Konishi H, et al. Biochem Biophys Res Commun. 1994 Dec 30;205(3):1770-5. doi: 10.1006/bbrc.1994.2874. Biochem Biophys Res Commun. 1994. PMID: 7811263

5

Identification of myosin II as a binding protein to the PH domain of protein kinase B.

Tanaka M, Konishi H, Touhara K, Sakane F, Hirata M, Ono Y, Kikkawa U. Tanaka M, et al. Among authors: konishi h. Biochem Biophys Res Commun. 1999 Feb 5;255(1):169-74. doi: 10.1006/bbrc.1999.0162. Biochem Biophys Res Commun. 1999. PMID: 10082674

6

Identification of protein kinase B (PKB) as a phosphatidylinositol 3,4,5-trisphosphate binding protein in Dictyostelium discoideum.

Tanaka K, Adachi H, Konishi H, Iwamatsu A, Ohkawa K, Shirai T, Nagata S, Kikkawa U, Fukui Y. Tanaka K, et al. Among authors: konishi h. Biosci Biotechnol Biochem. 1999 Feb;63(2):368-72. doi: 10.1271/bbb.63.368. Biosci Biotechnol Biochem. 1999. PMID: 10192918 Free article.

7

Activation of protein kinase C by tyrosine phosphorylation in response to H2O2.

Konishi H, Tanaka M, Takemura Y, Matsuzaki H, Ono Y, Kikkawa U, Nishizuka Y. Konishi H, et al. Proc Natl Acad Sci U S A. 1997 Oct 14;94(21):11233-7. doi: 10.1073/pnas.94.21.11233. Proc Natl Acad Sci U S A. 1997. PMID: 9326592 Free PMC article.

8

Distinct specificity in the binding of inositol phosphates by pleckstrin homology domains of pleckstrin, RAC-protein kinase, diacylglycerol kinase and a new 130 kDa protein.

Takeuchi H, Kanematsu T, Misumi Y, Sakane F, Konishi H, Kikkawa U, Watanabe Y, Katan M, Hirata M. Takeuchi H, et al. Among authors: konishi h. Biochim Biophys Acta. 1997 Dec 12;1359(3):275-85. doi: 10.1016/s0167-4889(97)00109-2. Biochim Biophys Acta. 1997. PMID: 9434133 Free article.

9

Three distinct mechanisms for translocation and activation of the delta subspecies of protein kinase C.

Ohmori S, Shirai Y, Sakai N, Fujii M, Konishi H, Kikkawa U, Saito N. Ohmori S, et al. Among authors: konishi h. Mol Cell Biol. 1998 Sep;18(9):5263-71. doi: 10.1128/MCB.18.9.5263. Mol Cell Biol. 1998. PMID: 9710611 Free PMC article.

10

Opposing effects of protein kinase C delta and protein kinase B alpha on H(2)O(2)-induced apoptosis in CHO cells.

Konishi H, Matsuzaki H, Takaishi H, Yamamoto T, Fukunaga M, Ono Y, Kikkawa U. Konishi H, et al. Biochem Biophys Res Commun. 1999 Nov 2;264(3):840-6. doi: 10.1006/bbrc.1999.1579. Biochem Biophys Res Commun. 1999. PMID: 10544018

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