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Discovery of aminothiazole inhibitors of cyclin-dependent kinase 2: synthesis, X-ray crystallographic analysis, and biological activities.
Kim KS, Kimball SD, Misra RN, Rawlins DB, Hunt JT, Xiao HY, Lu S, Qian L, Han WC, Shan W, Mitt T, Cai ZW, Poss MA, Zhu H, Sack JS, Tokarski JS, Chang CY, Pavletich N, Kamath A, Humphreys WG, Marathe P, Bursuker I, Kellar KA, Roongta U, Batorsky R, Mulheron JG, Bol D, Fairchild CR, Lee FY, Webster KR. Kim KS, et al. Among authors: bursuker i. J Med Chem. 2002 Aug 29;45(18):3905-27. doi: 10.1021/jm0201520. J Med Chem. 2002. PMID: 12190313
1H-Pyrazolo[3,4-b]pyridine inhibitors of cyclin-dependent kinases.
Misra RN, Rawlins DB, Xiao HY, Shan W, Bursuker I, Kellar KA, Mulheron JG, Sack JS, Tokarski JS, Kimball SD, Webster KR. Misra RN, et al. Among authors: bursuker i. Bioorg Med Chem Lett. 2003 Mar 24;13(6):1133-6. doi: 10.1016/s0960-894x(03)00034-9. Bioorg Med Chem Lett. 2003. PMID: 12643928
Nitrogen-appended N-alkylsulfonamides as inhibitors of gamma-secretase.
Bergstrom CP, Sloan CP, Wang HH, Parker MF, Smith DW, Zheng M, Hansel SB, Polson CT, Barber LE, Bursuker I, Guss VL, Corsa JA, Barten DM, Felsenstein KM, Roberts SB. Bergstrom CP, et al. Among authors: bursuker i. Bioorg Med Chem Lett. 2008 Jan 1;18(1):175-8. doi: 10.1016/j.bmcl.2007.10.105. Epub 2007 Nov 1. Bioorg Med Chem Lett. 2008. PMID: 18023581
Fusaricide, a new cytotoxic N-hydroxypyridone from Fusarium sp.
McBrien KD, Gao Q, Huang S, Klohr SE, Wang RR, Pirnik DM, Neddermann KM, Bursuker I, Kadow KF, Leet JE. McBrien KD, et al. Among authors: bursuker i. J Nat Prod. 1996 Dec;59(12):1151-3. doi: 10.1021/np960521t. J Nat Prod. 1996. PMID: 8988601
39 results