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In vivo measurement of QT prolongation, dispersion and arrhythmogenesis: application to the preclinical cardiovascular safety pharmacology of a new chemical entity.
De Clerck F, Van de Water A, D'Aubioul J, Lu HR, van Rossem K, Hermans A, Van Ammel K. De Clerck F, et al. Among authors: van ammel k, van de water a, van rossem k. Fundam Clin Pharmacol. 2002 Apr;16(2):125-40. doi: 10.1046/j.1472-8206.2002.00081.x. Fundam Clin Pharmacol. 2002. PMID: 12031065 Review.
Differential effects of thromboxane A2 synthase inhibition, singly or combined with thromboxane A2/prostaglandin endoperoxide receptor antagonism, on occlusive thrombosis elicited by endothelial cell injury or by deep vascular damage in canine coronary arteries.
Vandeplassche G, Hemans C, Van de Water A, Xhonneux R, Wouters L, Van Ammel K, De Clerck F. Vandeplassche G, et al. Among authors: van ammel k, van de water a. Circ Res. 1991 Aug;69(2):313-24. doi: 10.1161/01.res.69.2.313. Circ Res. 1991. PMID: 1830517
The fentanyl/etomidate-anaesthetised beagle (FEAB) dog: a versatile in vivo model in cardiovascular safety research.
Van Deuren B, Van Ammel K, Somers Y, Cools F, Straetemans R, van der Linde HJ, Gallacher DJ. Van Deuren B, et al. Among authors: van ammel k, van der linde hj. J Pharmacol Toxicol Methods. 2009 Jul-Aug;60(1):11-23. doi: 10.1016/j.vascn.2009.04.195. Epub 2009 May 5. J Pharmacol Toxicol Methods. 2009. PMID: 19422925 Review.
An improved method to correct the QT interval of the electrocardiogram for changes in heart rate. Journal of Pharmacological Methods, 22, 207-217.; van der Linde, H.J., Van Deuren, B., Teisman, A., Towart, R. & Gallacher, D.J. (2008). The effect of changes in co …
An improved method to correct the QT interval of the electrocardiogram for changes in heart rate. Journal of Pharmacological Methods, 22, 20 …
25 results