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A consensus tetrapeptide selected by phage display adopts the conformation of a dominant discontinuous epitope of a monoclonal anti-VWF antibody that inhibits the von Willebrand factor-collagen interaction.
Vanhoorelbeke K, Depraetere H, Romijn RA, Huizinga EG, De Maeyer M, Deckmyn H. Vanhoorelbeke K, et al. Among authors: deckmyn h. J Biol Chem. 2003 Sep 26;278(39):37815-21. doi: 10.1074/jbc.M304289200. Epub 2003 Jul 10. J Biol Chem. 2003. PMID: 12855711 Free article.
Von Willebrand factor: drug and drug target.
De Meyer SF, De Maeyer B, Deckmyn H, Vanhoorelbeke K. De Meyer SF, et al. Among authors: deckmyn h. Cardiovasc Hematol Disord Drug Targets. 2009 Mar;9(1):9-20. doi: 10.2174/187152909787581327. Cardiovasc Hematol Disord Drug Targets. 2009. PMID: 19275573 Review.
von Willebrand factor to the rescue.
De Meyer SF, Deckmyn H, Vanhoorelbeke K. De Meyer SF, et al. Among authors: deckmyn h. Blood. 2009 May 21;113(21):5049-57. doi: 10.1182/blood-2008-10-165621. Epub 2009 Mar 24. Blood. 2009. PMID: 19318682 Free article. Review.
Human platelets produced in nonobese diabetic/severe combined immunodeficient (NOD/SCID) mice upon transplantation of human cord blood CD34(+) cells are functionally active in an ex vivo flow model of thrombosis.
Salles II, Thijs T, Brunaud C, De Meyer SF, Thys J, Vanhoorelbeke K, Deckmyn H. Salles II, et al. Among authors: deckmyn h. Blood. 2009 Dec 3;114(24):5044-51. doi: 10.1182/blood-2009-02-205989. Epub 2009 Sep 9. Blood. 2009. PMID: 19741191 Free article.
261 results