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Hydroxychloroquine inhibits hemolysis-induced arterial thrombosis ex vivo and improves lung perfusion in hemin-treated mice.
Bourne JH, Perrella G, El-Awaisi J, Terry LV, Tinkova V, Hogg RL, Gant P, Grygielska B, Kalia N, Kavanagh D, Brill A, Dimitrov JD, Watson SP, Rayes J. Bourne JH, et al. Among authors: watson sp. J Thromb Haemost. 2024 Apr 24:S1538-7836(24)00226-5. doi: 10.1016/j.jtha.2024.04.008. Online ahead of print. J Thromb Haemost. 2024. PMID: 38670315 Free article.
PF4 activates the c-Mpl-Jak2 pathway in platelets.
Buka RJ, Montague SJ, Moran LA, Martin EM, Slater A, Watson SP, Nicolson PLR. Buka RJ, et al. Among authors: watson sp. Blood. 2024 Jan 4;143(1):64-69. doi: 10.1182/blood.2023020872. Blood. 2024. PMID: 37883794 Free PMC article.
Trivalent nanobody-based ligands mediate powerful activation of GPVI, CLEC-2, and PEAR1 in human platelets whereas FcγRIIA requires a tetravalent ligand.
Martin EM, Clark JC, Montague SJ, Morán LA, Di Y, Bull LJ, Whittle L, Raka F, Buka RJ, Zafar I, Kardeby C, Slater A, Watson SP. Martin EM, et al. Among authors: watson sp. J Thromb Haemost. 2024 Jan;22(1):271-285. doi: 10.1016/j.jtha.2023.09.026. Epub 2023 Oct 9. J Thromb Haemost. 2024. PMID: 37813196 Free article.
Amplified inhibition of atherosclerotic plaque-induced platelet activation by glenzocimab with dual antiplatelet therapy.
Alenazy FO, Harbi MH, Kavanagh DP, Price J, Brady P, Hargreaves O, Harrison P, Slater A, Tiwari A, Nicolson PLR, Connolly DL, Kirchhof P, Kalia N, Jandrot-Perrus M, Mangin PH, Watson SP, Thomas MR. Alenazy FO, et al. Among authors: watson sp. J Thromb Haemost. 2023 Nov;21(11):3236-3251. doi: 10.1016/j.jtha.2023.07.018. Epub 2023 Aug 3. J Thromb Haemost. 2023. PMID: 37541591 Free article.
Antagonistic Roles of Human Platelet Integrin αIIbβ3 and Chemokines in Regulating Neutrophil Activation and Fate on Arterial Thrombi Under Flow.
Schönichen C, Montague SJ, Brouns SLN, Burston JJ, Cosemans JMEM, Jurk K, Kehrel BE, Koenen RR, Ní Áinle F, O'Donnell VB, Soehnlein O, Watson SP, Kuijpers MJE, Heemskerk JWM, Nagy M. Schönichen C, et al. Among authors: watson sp. Arterioscler Thromb Vasc Biol. 2023 Sep;43(9):1700-1712. doi: 10.1161/ATVBAHA.122.318767. Epub 2023 Jul 6. Arterioscler Thromb Vasc Biol. 2023. PMID: 37409530 Free PMC article.
488 results