Differential susceptibilities of Holtzman and Sprague-Dawley rats to fetal death and placental dysfunction induced by 2,3,7,8-teterachlorodibenzo-p-dioxin (TCDD) despite the identical primary structure of the aryl hydrocarbon receptor.
Kawakami T, Ishimura R, Nohara K, Takeda K, Tohyama C, Ohsako S.
Kawakami T, et al. Among authors: ohsako s.
Toxicol Appl Pharmacol. 2006 May 1;212(3):224-36. doi: 10.1016/j.taap.2005.08.007. Epub 2005 Oct 3.
Toxicol Appl Pharmacol. 2006.
PMID: 16202437
A single oral dose of 2,3,7,8-tetrachlorodibenzo-p-dioin (TCDD) administered to pregnant Holtzman (HLZ) rats on gestational days 15 (GD15) caused placental dysfunction, resulting in fetal death (Ishimura, R., Ohsako, S., Miyabara, Y., Sakaue, M., Kawakami, T., Aoki, …
A single oral dose of 2,3,7,8-tetrachlorodibenzo-p-dioin (TCDD) administered to pregnant Holtzman (HLZ) rats on gestational days 15 (GD15) c …