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Single amino acid substitutions in kappa-conotoxin PVIIA disrupt interaction with the shaker K+ channel.
Jacobsen RB, Koch ED, Lange-Malecki B, Stocker M, Verhey J, Van Wagoner RM, Vyazovkina A, Olivera BM, Terlau H. Jacobsen RB, et al. Among authors: stocker m. J Biol Chem. 2000 Aug 11;275(32):24639-44. doi: 10.1074/jbc.C900990199. J Biol Chem. 2000. PMID: 10818087 Free article.
kappa-Conotoxin PVIIA (kappa-PVIIA), a 27-amino acid peptide with three disulfide cross-links, isolated from the venom of Conus purpurascens, is the first conopeptide shown to inhibit the Shaker K(+) channel (Terlau, H., Shon, K., Grilley, M., Stocker, M., St …
kappa-Conotoxin PVIIA (kappa-PVIIA), a 27-amino acid peptide with three disulfide cross-links, isolated from the venom of Conus purpurascens …
kappa-Conotoxin PVIIA is a peptide inhibiting the shaker K+ channel.
Shon KJ, Stocker M, Terlau H, Stühmer W, Jacobsen R, Walker C, Grilley M, Watkins M, Hillyard DR, Gray WR, Olivera BM. Shon KJ, et al. Among authors: stocker m. J Biol Chem. 1998 Jan 2;273(1):33-8. doi: 10.1074/jbc.273.1.33. J Biol Chem. 1998. PMID: 9417043 Free article.
Specific enhancement of SK channel activity selectively potentiates the afterhyperpolarizing current I(AHP) and modulates the firing properties of hippocampal pyramidal neurons.
Pedarzani P, McCutcheon JE, Rogge G, Jensen BS, Christophersen P, Hougaard C, Strøbaek D, Stocker M. Pedarzani P, et al. Among authors: stocker m. J Biol Chem. 2005 Dec 16;280(50):41404-11. doi: 10.1074/jbc.M509610200. Epub 2005 Oct 20. J Biol Chem. 2005. PMID: 16239218 Free article.
317 results