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A common polymorphism acts as an intragenic modifier of mutant p53 behaviour.
Marin MC, Jost CA, Brooks LA, Irwin MS, O'Nions J, Tidy JA, James N, McGregor JM, Harwood CA, Yulug IG, Vousden KH, Allday MJ, Gusterson B, Ikawa S, Hinds PW, Crook T, Kaelin WG Jr. Marin MC, et al. Among authors: irwin ms. Nat Genet. 2000 May;25(1):47-54. doi: 10.1038/75586. Nat Genet. 2000. PMID: 10802655
Role for the p53 homologue p73 in E2F-1-induced apoptosis.
Irwin M, Marin MC, Phillips AC, Seelan RS, Smith DI, Liu W, Flores ER, Tsai KY, Jacks T, Vousden KH, Kaelin WG Jr. Irwin M, et al. Nature. 2000 Oct 5;407(6804):645-8. doi: 10.1038/35036614. Nature. 2000. PMID: 11034215
Regulatory feedback loop between TP73 and TRIM32.
Gonzalez-Cano L, Hillje AL, Fuertes-Alvarez S, Marques MM, Blanch A, Ian RW, Irwin MS, Schwamborn JC, Marín MC. Gonzalez-Cano L, et al. Among authors: irwin ms. Cell Death Dis. 2013 Jul 4;4(7):e704. doi: 10.1038/cddis.2013.224. Cell Death Dis. 2013. PMID: 23828567 Free PMC article.
Oncogenes induce and activate endogenous p73 protein.
Zaika A, Irwin M, Sansome C, Moll UM. Zaika A, et al. J Biol Chem. 2001 Apr 6;276(14):11310-6. doi: 10.1074/jbc.M005737200. Epub 2000 Dec 13. J Biol Chem. 2001. PMID: 11115495 Free article.
DeltaNp73: misunderstood protein?
Irwin MS. Irwin MS. Cancer Biol Ther. 2006 Jul;5(7):804-7. doi: 10.4161/cbt.5.7.3023. Epub 2006 Jul 14. Cancer Biol Ther. 2006. PMID: 16921261 No abstract available.
143 results