Otton SV - Search Results

1

Cytochrome P450 2D6 and treatment of codeine dependence.

Romach MK, Otton SV, Somer G, Tyndale RF, Sellers EM. Romach MK, et al. Among authors: otton sv. J Clin Psychopharmacol. 2000 Feb;20(1):43-5. doi: 10.1097/00004714-200002000-00008. J Clin Psychopharmacol. 2000. PMID: 10653207

2

Pharmacokinetics of dextromethorphan and metabolites in humans: influence of the CYP2D6 phenotype and quinidine inhibition.

Schadel M, Wu D, Otton SV, Kalow W, Sellers EM. Schadel M, et al. Among authors: otton sv. J Clin Psychopharmacol. 1995 Aug;15(4):263-9. doi: 10.1097/00004714-199508000-00005. J Clin Psychopharmacol. 1995. PMID: 7593709 Clinical Trial.

3

Inhibition of human cytochrome P450 2D6 (CYP2D6) by methadone.

Wu D, Otton SV, Sproule BA, Busto U, Inaba T, Kalow W, Sellers EM. Wu D, et al. Among authors: otton sv. Br J Clin Pharmacol. 1993 Jan;35(1):30-4. doi: 10.1111/j.1365-2125.1993.tb05666.x. Br J Clin Pharmacol. 1993. PMID: 8448065 Free PMC article.

4

Inhibition by fluoxetine of cytochrome P450 2D6 activity.

Otton SV, Wu D, Joffe RT, Cheung SW, Sellers EM. Otton SV, et al. Clin Pharmacol Ther. 1993 Apr;53(4):401-9. doi: 10.1038/clpt.1993.43. Clin Pharmacol Ther. 1993. PMID: 8477556

5

Effect of cytochrome P450 2D1 inhibition on hydrocodone metabolism and its behavioral consequences in rats.

Tomkins DM, Otton SV, Joharchi N, Li NY, Balster RF, Tyndale RF, Sellers EM. Tomkins DM, et al. Among authors: otton sv. J Pharmacol Exp Ther. 1997 Mar;280(3):1374-82. J Pharmacol Exp Ther. 1997. PMID: 9067326

6

Inhibition of cytochrome P450 2D6 metabolism of hydrocodone to hydromorphone does not importantly affect abuse liability.

Kaplan HL, Busto UE, Baylon GJ, Cheung SW, Otton SV, Somer G, Sellers EM. Kaplan HL, et al. Among authors: otton sv. J Pharmacol Exp Ther. 1997 Apr;281(1):103-8. J Pharmacol Exp Ther. 1997. PMID: 9103485 Clinical Trial.

7

The potential role of the cytochrome P-450 2D6 pharmacogenetic polymorphism in drug abuse.

Sellers EM, Otton SV, Tyndale RF. Sellers EM, et al. Among authors: otton sv. NIDA Res Monogr. 1997;173:6-26. NIDA Res Monogr. 1997. PMID: 9260180 Review. No abstract available.

8

CYP2D6 inhibition in patients treated with sertraline.

Sproule BA, Otton SV, Cheung SW, Zhong XH, Romach MK, Sellers EM. Sproule BA, et al. Among authors: otton sv. J Clin Psychopharmacol. 1997 Apr;17(2):102-6. doi: 10.1097/00004714-199704000-00007. J Clin Psychopharmacol. 1997. PMID: 10950472

9

Catalytic and immunologic similarities between monkey and human liver cytochrome P-450db1 (human cytochrome P-450 2D6).

Otton SV, Tyndale RF, Wu D, Inaba T, Kalow W, Sellers EM. Otton SV, et al. Drug Metab Dispos. 1992 Jan-Feb;20(1):1-5. Drug Metab Dispos. 1992. PMID: 1346982

10

CYP2D6 phenotype determines the metabolic conversion of hydrocodone to hydromorphone.

Otton SV, Schadel M, Cheung SW, Kaplan HL, Busto UE, Sellers EM. Otton SV, et al. Clin Pharmacol Ther. 1993 Nov;54(5):463-72. doi: 10.1038/clpt.1993.177. Clin Pharmacol Ther. 1993. PMID: 7693389

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