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The oncogene product Vav is a crucial regulator of primary cytotoxic T cell responses but has no apparent role in CD28-mediated co-stimulation.
Penninger JM, Fischer KD, Sasaki T, Kozieradzki I, Le J, Tedford K, Bachmaier K, Ohashi PS, Bachmann MF. Penninger JM, et al. Among authors: kozieradzki i. Eur J Immunol. 1999 May;29(5):1709-18. doi: 10.1002/(SICI)1521-4141(199905)29:05<1709::AID-IMMU1709>3.0.CO;2-O. Eur J Immunol. 1999. PMID: 10359126 Free article.
Positive regulation of T cell activation and integrin adhesion by the adapter Fyb/Slap.
Griffiths EK, Krawczyk C, Kong YY, Raab M, Hyduk SJ, Bouchard D, Chan VS, Kozieradzki I, Oliveira-Dos-Santos AJ, Wakeham A, Ohashi PS, Cybulsky MI, Rudd CE, Penninger JM. Griffiths EK, et al. Among authors: kozieradzki i. Science. 2001 Sep 21;293(5538):2260-3. doi: 10.1126/science.1063397. Science. 2001. PMID: 11567140
Angiotensin-converting enzyme 2 is an essential regulator of heart function.
Crackower MA, Sarao R, Oudit GY, Yagil C, Kozieradzki I, Scanga SE, Oliveira-dos-Santos AJ, da Costa J, Zhang L, Pei Y, Scholey J, Ferrario CM, Manoukian AS, Chappell MC, Backx PH, Yagil Y, Penninger JM. Crackower MA, et al. Among authors: kozieradzki i. Nature. 2002 Jun 20;417(6891):822-8. doi: 10.1038/nature00786. Nature. 2002. PMID: 12075344
Impaired CD28-mediated interleukin 2 production and proliferation in stress kinase SAPK/ERK1 kinase (SEK1)/mitogen-activated protein kinase kinase 4 (MKK4)-deficient T lymphocytes.
Nishina H, Bachmann M, Oliveira-dos-Santos AJ, Kozieradzki I, Fischer KD, Odermatt B, Wakeham A, Shahinian A, Takimoto H, Bernstein A, Mak TW, Woodgett JR, Ohashi PS, Penninger JM. Nishina H, et al. Among authors: kozieradzki i. J Exp Med. 1997 Sep 15;186(6):941-53. doi: 10.1084/jem.186.6.941. J Exp Med. 1997. PMID: 9294148 Free PMC article.
47 results