Varga SL - Search Results

1

Disposition and pharmacokinetics of the antimigraine drug, rizatriptan, in humans.

Vyas KP, Halpin RA, Geer LA, Ellis JD, Liu L, Cheng H, Chavez-Eng C, Matuszewski BK, Varga SL, Guiblin AR, Rogers JD. Vyas KP, et al. Among authors: varga sl. Drug Metab Dispos. 2000 Jan;28(1):89-95. Drug Metab Dispos. 2000. PMID: 10611145

2

Species differences in the metabolism of a potent HIV-1 reverse transcriptase inhibitor L-738,372. In vivo and in vitro studies in rats, dogs, monkeys, and human.

Prueksaritanont T, Balani SK, Dwyer LM, Ellis JD, Kauffman LR, Varga SL, Pitzenberger SM, Theoharides AD. Prueksaritanont T, et al. Among authors: varga sl. Drug Metab Dispos. 1995 Jul;23(7):688-95. Drug Metab Dispos. 1995. PMID: 7587955

3

Metabolism of 3-[2-(benzoxazol-2-yl)ethyl]-5-ethyl-6-methylpyridin-2 (1H)-one (L-696,229), an HIV-1 reverse transcriptase inhibitor, by rat liver slices and in humans.

Balani SK, Kauffman LR, Arison BH, Olah TV, Goldman ME, Varga SL, O'Brien JA, Ramjit HG, Rooney CS, Hoffman JM, et al. Balani SK, et al. Among authors: varga sl. Drug Metab Dispos. 1994 Mar-Apr;22(2):200-5. Drug Metab Dispos. 1994. PMID: 7516852

4

Biotransformation of 5-chloro-3-phenylthioindole-2-carboxamide (L-734,005) in rhesus monkeys and rat liver microsomes to a potent HIV-1 reverse transcriptase inhibitor.

Balani SK, Goldman ME, Kauffman LR, Varga SL, O'Brien JA, Smith SJ, Olah TV, Ramjit HG, Schorn TW, Pitzenberger SM, et al. Balani SK, et al. Among authors: varga sl. Drug Metab Dispos. 1993 Jul-Aug;21(4):598-604. Drug Metab Dispos. 1993. PMID: 7690697

5

Synthesis of 5-(1-H or 1-alkyl-5-oxopyrrolidin-3-yl)-8-hydroxy-[1,6]-naphthyridine-7-carboxamide inhibitors of HIV-1 integrase.

Melamed JY, Egbertson MS, Varga S, Vacca JP, Moyer G, Gabryelski L, Felock PJ, Stillmock KA, Witmer MV, Schleif W, Hazuda DJ, Leonard Y, Jin L, Ellis JD, Young SD. Melamed JY, et al. Bioorg Med Chem Lett. 2008 Oct 1;18(19):5307-10. doi: 10.1016/j.bmcl.2008.08.038. Epub 2008 Aug 14. Bioorg Med Chem Lett. 2008. PMID: 18774711

6

Design and synthesis of potent, selective, and orally bioavailable tetrasubstituted imidazole inhibitors of p38 mitogen-activated protein kinase.

Liverton NJ, Butcher JW, Claiborne CF, Claremon DA, Libby BE, Nguyen KT, Pitzenberger SM, Selnick HG, Smith GR, Tebben A, Vacca JP, Varga SL, Agarwal L, Dancheck K, Forsyth AJ, Fletcher DS, Frantz B, Hanlon WA, Harper CF, Hofsess SJ, Kostura M, Lin J, Luell S, O'Neill EA, O'Keefe SJ, et al. Liverton NJ, et al. Among authors: varga sl. J Med Chem. 1999 Jun 17;42(12):2180-90. doi: 10.1021/jm9805236. J Med Chem. 1999. PMID: 10377223

7

Nonpeptide alphavbeta3 antagonists. 8. In vitro and in vivo evaluation of a potent alphavbeta3 antagonist for the prevention and treatment of osteoporosis.

Hutchinson JH, Halczenko W, Brashear KM, Breslin MJ, Coleman PJ, Duong LT, Fernandez-Metzler C, Gentile MA, Fisher JE, Hartman GD, Huff JR, Kimmel DB, Leu CT, Meissner RS, Merkle K, Nagy R, Pennypacker B, Perkins JJ, Prueksaritanont T, Rodan GA, Varga SL, Wesolowski GA, Zartman AE, Rodan SB, Duggan ME. Hutchinson JH, et al. Among authors: varga sl. J Med Chem. 2003 Oct 23;46(22):4790-8. doi: 10.1021/jm030306r. J Med Chem. 2003. PMID: 14561098

8

Identification and quantitation of extractables from cellulose acetate butyrate (CAB) and estimation of their in vivo exposure levels.

Ma D, Wasylaschuk WR, Beasley C, Zhao ZZ, Harmon PA, Ballard JM, Pitzenberger SM, Varga SL, Reed RA. Ma D, et al. Among authors: varga sl. J Pharm Biomed Anal. 2004 Jun 29;35(4):779-88. doi: 10.1016/j.jpba.2004.03.004. J Pharm Biomed Anal. 2004. PMID: 15193722

9

Bismacrocyclic inhibitors of hepatitis C NS3/4a protease.

McCauley JA, Rudd MT, Nguyen KT, McIntyre CJ, Romano JJ, Bush KJ, Varga SL, Ross CW 3rd, Carroll SS, DiMuzio J, Stahlhut MW, Olsen DB, Lyle TA, Vacca JP, Liverton NJ. McCauley JA, et al. Among authors: varga sl. Angew Chem Int Ed Engl. 2008;47(47):9104-7. doi: 10.1002/anie.200803298. Angew Chem Int Ed Engl. 2008. PMID: 18925594 No abstract available.

10

Synthesis and pharmacological evaluation of a series of dibenzo[a,d]cycloalkenimines as N-methyl-D-aspartate antagonists.

Thompson WJ, Anderson PS, Britcher SF, Lyle TA, Thies JE, Magill CA, Varga SL, Schwering JE, Lyle PA, Christy ME, et al. Thompson WJ, et al. Among authors: varga sl. J Med Chem. 1990 Feb;33(2):789-808. doi: 10.1021/jm00164a052. J Med Chem. 1990. PMID: 1688947

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