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Pan-active imidazolopiperazine antimalarials target the Plasmodium falciparum intracellular secretory pathway.
LaMonte GM, Rocamora F, Marapana DS, Gnädig NF, Ottilie S, Luth MR, Worgall TS, Goldgof GM, Mohunlal R, Santha Kumar TR, Thompson JK, Vigil E, Yang J, Hutson D, Johnson T, Huang J, Williams RM, Zou BY, Cheung AL, Kumar P, Egan TJ, Lee MCS, Siegel D, Cowman AF, Fidock DA, Winzeler EA. LaMonte GM, et al. Nat Commun. 2020 Apr 14;11(1):1780. doi: 10.1038/s41467-020-15440-4. Nat Commun. 2020. PMID: 32286267 Free PMC article.
Airway IL-1β is related to disease severity and mucociliary function in bronchiectasis.
Perea L, Bottier M, Cant E, Richardson H, Dicker AJ, Shuttleworth M, Giam YH, Abo-Leyah H, Finch S, Huang JT, Shteinberg M, Goeminne PC, Polverino E, Altenburg J, Blasi F, Welte T, Aliberti S, Sibila O, Chalmers JD, Shoemark A. Perea L, et al. Among authors: huang jt. Eur Respir J. 2024 May 29:2301966. doi: 10.1183/13993003.01966-2023. Online ahead of print. Eur Respir J. 2024. PMID: 38811046
Endotypes of Exacerbation in Bronchiectasis: An Observational Cohort Study.
Gao Y, Richardson H, Dicker AJ, Barton A, Kuzmanova E, Shteinberg M, Perea L, Goeminne PC, Cant E, Hennayake C, Pollock J, Abo Leyah H, Choi H, Polverino E, Blasi F, Welte T, Aliberti S, Long M, Shoemark A, Sibila O, Huang JTJ, Chalmers JD. Gao Y, et al. Among authors: huang jtj. Am J Respir Crit Care Med. 2024 May 8. doi: 10.1164/rccm.202310-1729OC. Online ahead of print. Am J Respir Crit Care Med. 2024. PMID: 38717347
468 results