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2021 | 1 |
2023 | 1 |
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Development of AAV-delivered broadly neutralizing anti-human ACE2 antibodies against SARS-CoV-2 variants.
Mol Ther. 2023 Nov 1;31(11):3322-3336. doi: 10.1016/j.ymthe.2023.09.002. Epub 2023 Sep 9.
Mol Ther. 2023.
PMID: 37689971
Free article.
The ongoing evolution of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), resulting in the emergence of new variants that are resistant to existing vaccines and therapeutic antibodies, has raised the need for novel strategies to combat the persistent global CO …
The ongoing evolution of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), resulting in the emergence of new variants that are r …
Rapid generation of mouse model for emerging infectious disease with the case of severe COVID-19.
Sun CP, Jan JT, Wang IH, Ma HH, Ko HY, Wu PY, Kuo TJ, Liao HN, Lan YH, Sie ZL, Chen YH, Ko YA, Liao CC, Chen LY, Lee IJ, Tsung SI, Lai YJ, Chiang MT, Liang JJ, Liu WC, Wang JR, Yuan JP, Lin YS, Tsai YC, Hsieh SL, Li CW, Wu HC, Ko TM, Lin YL, Tao MH.
Sun CP, et al. Among authors: tsung si.
PLoS Pathog. 2021 Aug 11;17(8):e1009758. doi: 10.1371/journal.ppat.1009758. eCollection 2021 Aug.
PLoS Pathog. 2021.
PMID: 34379705
Free PMC article.
Upon virus challenge, generated AAV/hACE2 mice showed pathophysiology closely mimicking the patients with severe COVID-19. The efficacy of a novel therapeutic antibody cocktail RBD-chAbs for COVID-19 was tested and confirmed by using this AAV/hACE2 mouse model, further dem …
Upon virus challenge, generated AAV/hACE2 mice showed pathophysiology closely mimicking the patients with severe COVID-19. The efficacy of a …
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