Cloning and characterization of a gene cluster from Streptomyces cyanogenus S136 probably involved in landomycin biosynthesis

FEMS Microbiol Lett. 1999 Jan 15;170(2):381-7. doi: 10.1111/j.1574-6968.1999.tb13398.x.

Abstract

From a cosmid library of Streptomyces cyanogenus S136, DNA fragments encompassing approximately 35 kb of the presumed landomycin biosynthetic gene cluster were identified and sequenced, revealing 32 open reading frames most of which could be assigned through data base comparison.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Aminoglycosides*
  • Anti-Bacterial Agents / biosynthesis*
  • Base Sequence
  • Cloning, Molecular
  • Genes, Bacterial*
  • Molecular Sequence Data
  • Open Reading Frames
  • Streptomyces / chemistry
  • Streptomyces / genetics*

Substances

  • Aminoglycosides
  • Anti-Bacterial Agents
  • landomycin A

Associated data

  • GENBANK/AF080235