Demographic characteristics of zipeprol-associated deaths in Korea

Arch Pharm Res. 1998 Jun;21(3):286-90. doi: 10.1007/BF02975289.

Abstract

The abuse of zipeprol, an antitussive agent, was found to be most prevalent among young people in Korea. Because abusers take large doses of this drug for its hallucinogenic effects, fatalities from zipeprol overdose abuse have been on the rise since 1991. Since 1991, a total of 69 zipeprol-related deaths have occurred throughout the nation. A demographic study shows that in ninety six percent of cases involving ziperol alone, the victims were in their teens and twenties. The male/female ratio in zipeprol related death was 3.5:1. Most of these zipeprol-associated deaths occurred in the larger cities of Seoul and Inchon. The blood concentration of zipeprol ranged from 0.8 to 38.3 micrograms/mL in single drug involved deaths, while zipeprol varied from 0.1 to 35.3 micrograms/mL in zipeprol and dextromethorphan victims.

MeSH terms

  • Adolescent
  • Adult
  • Age Factors
  • Antitussive Agents / poisoning*
  • Calibration
  • Chromatography, Gas
  • Dextromethorphan / poisoning
  • Drug Overdose / mortality
  • Female
  • Humans
  • Indicators and Reagents
  • Korea / epidemiology
  • Male
  • Piperazines / poisoning*
  • Sex Factors
  • Substance-Related Disorders / mortality*

Substances

  • Antitussive Agents
  • Indicators and Reagents
  • Piperazines
  • Dextromethorphan
  • zipeprol