Suprasellar germinoma associated with Cushing's disease and diabetes insipidus in a child

Pediatr Neurosurg. 1998 Jul;29(1):19-22. doi: 10.1159/000028679.

Abstract

Cushing's disease is described in a child with a suprasellar germinoma. The patient presented with all of the classic stigmata of Cushing's disease as well as diabetes insipidus, but after surgical resection of the lesion was found to have pathology incompatible with an ACTH-secreting tumor. We believe that this is the first reported incidence of Cushing's disease associated with a suprasellar germinoma. The implications of this unusual association are discussed.

Publication types

  • Case Reports

MeSH terms

  • Adolescent
  • Adult
  • Brain Neoplasms / complications*
  • Brain Neoplasms / metabolism
  • Child
  • Child, Preschool
  • Cushing Syndrome / complications*
  • Cushing Syndrome / metabolism
  • Diabetes Insipidus / etiology*
  • Female
  • Germinoma / complications*
  • Germinoma / metabolism
  • Germinoma / pathology
  • Humans
  • Hydrocortisone / urine

Substances

  • Hydrocortisone