Pathobiology and clinical significance of molecular genetic findings in childhood tumors

Adv Pediatr. 1998:45:315-36.

Abstract

Molecular genetic determinants of malignant diseases in children are providing insights into the mechanisms of malignancies. These findings have improved diagnosis, treatment, and prognosis.

Publication types

  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, P.H.S.
  • Review

MeSH terms

  • Child
  • Genes, Tumor Suppressor / genetics
  • Humans
  • Leukemia, Myeloid / diagnosis
  • Leukemia, Myeloid / genetics
  • Lymphoma / diagnosis
  • Lymphoma / genetics
  • Neoplasms / diagnosis
  • Neoplasms / genetics*
  • Neoplasms / pathology
  • Neuroblastoma / diagnosis
  • Neuroblastoma / genetics
  • Oncogenes / genetics
  • Precursor Cell Lymphoblastic Leukemia-Lymphoma / diagnosis
  • Precursor Cell Lymphoblastic Leukemia-Lymphoma / genetics