Abstract
The use of antibiotic prophylaxis in oncological pharyngeal and laryngeal surgery has reduced the risk of postoperative wound infection, which decreases morbidity and health-care costs. We report the results of a prospective randomized study in our hospital comparing the effectiveness of two antibiotic protocols, amoxicillin-clavulanate and clindamycin plus gentamicin, both given for 24 hours, in patients who underwent clean-contaminated oncological surgery of the pharynx or larynx.
Publication types
-
Clinical Trial
-
Comparative Study
-
English Abstract
-
Randomized Controlled Trial
MeSH terms
-
Amoxicillin / administration & dosage
-
Amoxicillin / therapeutic use*
-
Clavulanic Acid / administration & dosage
-
Clavulanic Acid / therapeutic use*
-
Clindamycin / administration & dosage
-
Clindamycin / therapeutic use*
-
Drug Therapy, Combination / therapeutic use*
-
Gentamicins / administration & dosage
-
Gentamicins / therapeutic use*
-
Humans
-
Laryngeal Neoplasms / surgery*
-
Laryngectomy / methods*
-
Male
-
Neck Dissection*
-
Pharyngeal Neoplasms / surgery*
-
Pharyngectomy / methods*
-
Preanesthetic Medication*
-
Prospective Studies
-
Risk Factors
-
Surgical Wound Infection / prevention & control*
-
Treatment Outcome
Substances
-
Gentamicins
-
Clavulanic Acid
-
Clindamycin
-
Amoxicillin