The statistical correlation between the locations of hot spots at the surface of Earth and the distribution of ultra-low-velocity zones at the base of the mantle has about a 1 percent chance of arising randomly. This correlation is more significant than that between hot spots and negative velocity anomalies in tomographic models of deep mantle compressional and shear velocity. This correlation is consistent with the notion that many hot spots originate in a low-velocity, probably partially molten layer at the core-mantle boundary and undergo little lateral deflection on ascent.