[Parameters of cellular immunity in lung cancer patients with different types of adaptation reactions during polychemotherapy]

Vopr Onkol. 1998;44(2):164-6.
[Article in Russian]

Abstract

A relationship between cellular immunity and general adaptation syndrome in the course of CAM polychemotherapy has been investigated. The results point to a lack of lymphopenia, lower levels of T-suppressors and higher instability of immunological indices in patients showing increased activation reaction and maximum antitumor resistance during cytostatic therapy, unlike in those in stress. This opens an opportunity for correction.

Publication types

  • English Abstract

MeSH terms

  • Adult
  • Aged
  • Antineoplastic Combined Chemotherapy Protocols / immunology*
  • Antineoplastic Combined Chemotherapy Protocols / therapeutic use
  • Cyclophosphamide / immunology
  • Doxorubicin / immunology
  • Female
  • Humans
  • Lung Neoplasms / drug therapy*
  • Lung Neoplasms / immunology*
  • Lymphocytes / drug effects*
  • Male
  • Methotrexate / immunology
  • Middle Aged
  • T-Lymphocytes / drug effects

Substances

  • Doxorubicin
  • Cyclophosphamide
  • Methotrexate

Supplementary concepts

  • CAM combination