The erythrocyte oxy- and deoxygenation kinetics and the influence of the perfluorocarbon emulsions (PFCE) on the blood were studied using the device modeling blood circulation in the organism. It was found that a small additive of PFCE changed the oxygen transport in the erythrocyte-plasma-tissues. The oxygen-carrying properties of erythrocytes of PFCE-blood system are differ from ones of pure blood.