Epidermal growth factor enhancement of skin tumor induction in mice

Experientia. 1976;32(7):913-5. doi: 10.1007/BF02003764.

Abstract

Subcutaneous injection of epidermal growth factor 1. significantly shortened the latency period for the appearance of methylcholanthrene induced skin tumors and 2. increased the average number of papillomas elicited per mouse in both the Swiss Webster and C3HeB/FeJ strains.

Publication types

  • Research Support, U.S. Gov't, Non-P.H.S.
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Animals
  • Female
  • Growth Substances*
  • Methylcholanthrene
  • Mice
  • Mice, Inbred C3H
  • Papilloma / chemically induced
  • Peptides*
  • Skin Neoplasms / chemically induced*
  • Time Factors

Substances

  • Growth Substances
  • Peptides
  • Methylcholanthrene