The Synthesis of Phycopsisenone, a New Phenolic Secondary Metabolite from the Sponge Phycopsis sp

GL Kad; V Singh V; A Khurana; J Singh

doi:10.1021/np970394g

The Synthesis of Phycopsisenone, a New Phenolic Secondary Metabolite from the Sponge Phycopsis sp

J Nat Prod. 1998 Feb 27;61(2):297-8. doi: 10.1021/np970394g.

Authors

GL Kad¹, V Singh V, A Khurana, J Singh

Affiliation

¹ Department of Chemistry, Panjab University, Chandigarh 160014, India.

PMID: 9548864
DOI: 10.1021/np970394g

Abstract

A short first total synthesis of phycopsisenone (1) utilizing microwave irradiation-induced aldol condensation and TiCl4-catalyzed reaction of silyl enol ether (3) with acetone as key steps has been achieved in 29.4% overall yield.