Inteins in mycobacterial GyrA are a taxonomic character

Microbiology (Reading). 1998 Feb:144 ( Pt 2):589-591. doi: 10.1099/00221287-144-2-589.

Abstract

The A subunit of DNA gyrase in mycobacteria is frequently subjected to splicing events as its gene, gyrA, harbours an insertion encoding an intein. Investigation of a number of different isolates of Mycobacterium kansasii, Mycobacterium malmoense, Mycobacterium marinum, Mycobacterium ulcerans and Mycobacterium xenopi demonstrated that the presence of GyrA inteins is not random but a taxonomic character specific for a given taxon at a species or subspecies level.

MeSH terms

  • Bacterial Proteins / analysis*
  • Bacterial Proteins / genetics*
  • Classification
  • DNA Gyrase
  • DNA Topoisomerases, Type II / genetics*
  • DNA, Bacterial / analysis
  • DNA, Bacterial / genetics
  • Molecular Sequence Data
  • Mycobacterium / classification*
  • Mycobacterium / genetics
  • Nontuberculous Mycobacteria / classification*
  • Nontuberculous Mycobacteria / genetics
  • Polymerase Chain Reaction
  • RNA, Ribosomal, 16S / genetics

Substances

  • Bacterial Proteins
  • DNA, Bacterial
  • RNA, Ribosomal, 16S
  • pps1 protein, Mycobacterium sp.
  • DNA Gyrase
  • DNA Topoisomerases, Type II

Associated data

  • GENBANK/AJ002066