[Penetrating duodenal ulcer as a complication of a hepatic artery port catheter in hepatic metastasis of sigmoid carcinoma]

Med Klin (Munich). 1997 Nov 15;92(11):680-2. doi: 10.1007/BF03044825.
[Article in German]

Abstract

Case report: We report a typical complication of hepatic artery infusion therapy (HAI) in a patient with colon cancer metastatic to the liver. One year after the last HAI-therapy the patient presented with upper gastrointestinal bleeding. Endoscopy showed a large duodenic ulcer penetrating into an adjacent hepatic colon cancer metastasis. The hepatic artery catheter was visible at the ground of the duodenic ulcer.

Conclusion: Thirty-five percent of patients under HAI-therapy develop gastric/duodenic ulcers. The severity of the HAI complication presented here, however, is quite uncommon.

Publication types

  • Case Reports
  • English Abstract

MeSH terms

  • Adenocarcinoma / drug therapy
  • Adenocarcinoma / secondary*
  • Aged
  • Antineoplastic Combined Chemotherapy Protocols / administration & dosage
  • Antineoplastic Combined Chemotherapy Protocols / adverse effects*
  • Catheters, Indwelling*
  • Duodenal Ulcer / chemically induced*
  • Duodenal Ulcer / pathology
  • Duodenum / drug effects
  • Duodenum / pathology
  • Endoscopy, Gastrointestinal
  • Fluorouracil / administration & dosage
  • Fluorouracil / adverse effects*
  • Humans
  • Infusions, Intra-Arterial / instrumentation*
  • Intestinal Mucosa / drug effects
  • Intestinal Mucosa / pathology
  • Leucovorin / administration & dosage
  • Leucovorin / adverse effects*
  • Liver Neoplasms / drug therapy
  • Liver Neoplasms / secondary*
  • Male
  • Peptic Ulcer Perforation / chemically induced*
  • Peptic Ulcer Perforation / pathology
  • Sigmoid Neoplasms / drug therapy*

Substances

  • Leucovorin
  • Fluorouracil