Randomized, controlled, clinical trial of rice versus glucose oral rehydration solutions in infants and young children with acute watery diarrhoea

Acta Paediatr. 1997 Dec;86(12):1308-11. doi: 10.1111/j.1651-2227.1997.tb14903.x.

Abstract

A randomized clinical trial was carried out to compare a packaged ready-to-mix rice oral rehydration solution (ORS) to the standard glucose ORS for the treatment of childhood diarrhoea. Children were of either gender, aged 3-35 months, presenting with a history of watery diarrhoea for 72 h or less. The main outcomes examined were stool output, ORS intake, duration of diarrhoea and nutritional recovery during follow-up at 16 d of illness. Stool output in the first 24 h (106 vs 107 g kg(-1)), ORS intake in clinic (93 vs 102 ml per motion) and duration of diarrhoea (88 h vs 81 h) were similar in the two treatment groups. The few episodes that became persistent were similar (2%) in the two groups. The weight gain during follow-up was similar in the two ORS groups.

Publication types

  • Clinical Trial
  • Randomized Controlled Trial
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Acute Disease
  • Administration, Oral
  • Child, Preschool
  • Diarrhea / diagnosis
  • Diarrhea / physiopathology
  • Diarrhea / therapy*
  • Diarrhea, Infantile / diagnosis
  • Diarrhea, Infantile / physiopathology
  • Diarrhea, Infantile / therapy
  • Female
  • Glucose / therapeutic use*
  • Humans
  • India
  • Infant
  • Male
  • Oryza / therapeutic use*
  • Phytotherapy*
  • Rehydration Solutions / therapeutic use*
  • Treatment Outcome
  • Weight Gain

Substances

  • Rehydration Solutions
  • Glucose