Molecular analysis of foot-and-mouth disease type O viruses isolated in Saudi Arabia between 1983 and 1995

A R Samuel; N J Knowles; R P Kitching; S M Hafez

doi:10.1017/s0950268897008285

Molecular analysis of foot-and-mouth disease type O viruses isolated in Saudi Arabia between 1983 and 1995

Epidemiol Infect. 1997 Dec;119(3):381-9. doi: 10.1017/s0950268897008285.

Authors

A R Samuel¹, N J Knowles, R P Kitching, S M Hafez

Affiliation

¹ OIE/FAO World Reference Laboratory for Foot-and-Mouth Disease, Institute for Animal Health, Pirbright Laboratory, Surrey, UK.

Abstract

Partial nucleotide sequence of the capsid polypeptide coding gene 1D (VP1) was determined for 68 serotype O foot-and-mouth disease viruses isolated between 1983 and 1995 from outbreaks occurring in Saudi Arabia. The sequences were compared with previously published sequences: 14 viruses of Middle Eastern origin (isolated between 1987 and 1991); and with four vaccine virus strain sequences, three originating from the Middle East (O1/Turkey/Manisa/69, O1/Sharquia/Egypt/72 and O1/Israel/2/85) and one from Europe (O1/BFS 1860/UK/67). The virus isolates from Saudi Arabia and the Middle East vaccine virus strains formed a related genetic group distinct from the European O1 virus. Within this large group 12 distinct genetic sublineages were observed.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Animals
Aphthovirus / classification
Aphthovirus / genetics*
Aphthovirus / isolation & purification
Cattle
Disease Outbreaks / veterinary*
Foot-and-Mouth Disease / epidemiology
Foot-and-Mouth Disease / virology*
Middle East / epidemiology
Saudi Arabia / epidemiology
Sequence Analysis, DNA
Sheep