Blue-yellow deficiency in workers exposed to low concentrations of organic solvents

Int Arch Occup Environ Health. 1997;70(6):407-12. doi: 10.1007/s004200050237.

Abstract

Objectives: To evaluate the effects of low concentrations of organic solvents on color vision.

Methods: Color vision was examined in 24 workers exposed to mixtures of solvents and in 24 control subjects. Exposure to mixtures was below the threshold-limit values. Color vision ability was assessed using the Ishihara plates (to screen for congenital dyschromatopsia), the Farnsworth panel D-15 test, the Lanthony desaturated panel D-15 test, and the Standard Pseudoisochromatic Plates part 2 (SPP2 test).

Results: The comparatively less sensitive Farnsworth panel D-15 test failed to show any difference between the groups, but the Lanthony panel D-15 desaturated test as well as the SPP2 test showed a significant impairment in the exposed group. Errors were of the blue-yellow type.

Conclusion: This study gives further evidence that even mixtures of organic solvents at concentrations below the threshold-limit values may impair color vision.

MeSH terms

  • Adult
  • Case-Control Studies
  • Color Vision Defects / chemically induced*
  • Humans
  • Logistic Models
  • Male
  • Occupational Exposure / adverse effects*
  • Psychophysiology / methods
  • Solvents / adverse effects*

Substances

  • Solvents