CD40 and its ligand in cell-mediated immunity

R J Noelle

doi:10.1007/978-3-0348-8857-8_4

CD40 and its ligand in cell-mediated immunity

Agents Actions Suppl. 1998:49:17-22. doi: 10.1007/978-3-0348-8857-8_4.

Author

R J Noelle¹

Affiliation

¹ Department of Microbiology, Dartmouth Medical School, Lebanon, NH 03756, USA.

PMID: 9426824
DOI: 10.1007/978-3-0348-8857-8_4

Abstract

CD40 and its ligand (gp39, CD40L, TBAM) is central to the control of thymus-dependent humoral immunity. However, in recent years it has become evident that CD40 signaling also is critical in the development of cell-mediated immune responses. How CD40 regulates cell-mediated immunity is discussed.

Publication types

Review

MeSH terms

Animals
Antigen-Presenting Cells
B-Lymphocytes / immunology
CD40 Antigens / immunology*
CD40 Ligand
Humans
Immunity, Cellular*
Membrane Glycoproteins / immunology
T-Lymphocytes

Substances

CD40 Antigens
Membrane Glycoproteins
CD40 Ligand